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CompletedNCT02727556Updated Apr 6, 2017

Physiological Response and Visual Attention to Visual Food Images in Healthy Subjects and in Functional Dyspepsia Patients

An interventional study of visual images in Functional Dyspepsia, sponsored by University Hospital Tuebingen. Completed at 1 site in Germany. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-04-06.

Sponsored by University Hospital Tuebingen · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Non-randomized
Ages
18 Years to 65 Years
Sex
All
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Study summary

In functional dyspepsia (FD), abnormal cognitive and emotional changes such increased sensitization, anxiety, and depression scores have been reported in addition to the peripheral changes in gastrointestinal tract functions. In this study, investigators will evaluate the activity of autonomic nervous system, emotional response, and visual attention to food and non-food images in 30 male and female FD patients and 30 age/gender-matched healthy volunteers. These data will provide a new finding of the influence of impaired cognitive processing of food on symptom generation in functional gastrointestinal disorder patients.

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Conditions studied

  • Functional Dyspepsia

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Keywords

  • skin conductance response
  • facial muscle activity
  • heart rate variability
  • eyetracking
03

In context

Dyspepsia

363 studies on the registry are indexed under Dyspepsia; 51 are open to participants now.

This study's planned enrollment of 30 is below the median of 87 across 297 interventional studies indexed under Dyspepsia.

Browse Dyspepsia studies →

Lead sponsor

University Hospital Tuebingen is the lead sponsor of 476 studies on the registry; 104 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Male and female, volunteering adults BMI: 18-25 kg/m² right-handed Age: 18-65 years Capacity to give informed consent For FD patients, Diagnosis of functional dyspepsia over the last 12 months certified by a medical record Inconspicuous gastroscopy during the last 6 months certified by a medical record

Exclusion criteria

Exclusion Criteria:

  • Visual impairment Severe psychiatric illness (e.g. schizophrenia, severe depression (BDI-II:29-63)), substance dependence and abuse Intake of antidepressants / antipsychotics
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Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Functional dyspepsia patient

    Visual stimuli of food and non-food images will be presented to patients. Non-food images include positive, neutral, negative emotional pictures.

    Behavioral: visual images

  • Experimental
    Healthy

    Visual stimuli of food and non-food images will be presented to participants. Non-food images include positive, neutral, negative emotional pictures.

    Behavioral: visual images

Interventions

  • Behavioralvisual images
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What researchers measure

Primary outcomes

  1. Psychological response

    Skin conductance response

    Time frame: 1-2 years

  2. Psychological response

    heart rate variability

    Time frame: 1-2 years

  3. Psychological response

    facial muscle contraction

    Time frame: 1-2 years

  4. visual attention

    eyemovement

    Time frame: 1-2 years

Secondary outcomes

  1. Subjective rating

    fullness (visual analog scale)

    Time frame: 1-2 years

  2. Subjective rating

    satiation (visual analog scale)

    Time frame: 1-2 years

  3. Subjective rating

    nausea (visual analog scale)

    Time frame: 1-2 years

  4. Subjective rating

    pain (visual analog scale)

    Time frame: 1-2 years

  5. Subjective rating

    mood (visual analog scale)

    Time frame: 1-2 years

07

Study locations

1 site
  • Psychosomatic Medicine and Psychotherapy Department, University of Tübingen, Tübingen, Germany
    Tübingen, 72070, Germany
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 6, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02727556
Lead sponsor
University Hospital Tuebingen
Responsible party
Inseon Lee (MS, University Hospital Tuebingen) — Principal investigator
First posted
Apr 4, 2016
Start date
Mar 2016
Primary completion
Apr 2017
Completion
Apr 2017
Last update
Apr 6, 2017

Study contacts

Paul Enck, Prof
principal investigator · Psychosomatic Medicine and Psychotherapy Department, University of Tübingen, Tübingen, Germany
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2017. You cannot join it, but the record below documents what was studied.

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