CClinicalTrials.gg
Status unknownNCT02721095Updated May 3, 2016

Efficacy of KCl Plus 0.9%NaCl Compare With KCl Plus 0.45%NaCl

A Phase 4 interventional study of KCl plus 0.9%NaCl and KCl plus 0.45%NaCl in Hypokalemia, sponsored by Phramongkutklao College of Medicine and Hospital. Status unknown at 1 site in Thailand. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-05-03.

Sponsored by Phramongkutklao College of Medicine and Hospital · Phase 4, Interventional, and Treatment

The sponsor has not verified this record recently (last verified May 2016), so the status shown — last known as Recruiting — may be out of date.
Phase
Phase 4
Study type
Interventional
Enrollment
84
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

evaluate efficacy and safety of IV administration of potassium chloride (KCl) plus 0.9%NaCl compare with KCl plus half-strength normal saline solution (0.45%NaCl) in correcting hypokalemia

Read the detailed description

Hypokalemia is frequently encountered in hospitalized patients. Intravenous (IV) potassium repletion with saline is preferred used for initial therapy. However, administration of normal saline (0.9%NaCl) usually provokes sodium and potassium diuresis, thus, it might delay reversal of the hypokalemia.

Object of this study : to evaluate efficacy and safety of IV administration of potassium chloride (KCl) plus 0.9%NaCl compare with KCl plus half-strength normal saline solution (0.45%NaCl) in correcting hypokalemia.

02

Conditions studied

  • Hypokalemia

Browse trials for

03

In context

Hypokalemia

26 studies on the registry are indexed under Hypokalemia; 5 are open to participants now.

This study's planned enrollment of 84 is above the median of 73 across 18 interventional studies indexed under Hypokalemia.

Browse Hypokalemia studies →

Lead sponsor

Phramongkutklao College of Medicine and Hospital is the lead sponsor of 36 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Serum K+ 2.5-3.49 mmol/L
  • No life threatening condition from hypokalemia

Exclusion criteria

Exclusion Criteria:

  • Pregnancy
  • Volume overload, heart failure
  • Hypotension
  • Acute kidney injury
  • Dysnatremia
  • K+ shift
  • Salt wasting nephropathy
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
84 participants (estimated)

Study arms

  • Experimental
    0.9%NaCl

    KCl plus 0.9%NaCl

    Other: KCl plus 0.9%NaCl

  • Active comparator
    0.45%NaCl

    KCl plus 0.45%NaCl

    Other: KCl plus 0.45%NaCl

Interventions

  • OtherKCl plus 0.9%NaCl

    comparison of KCl plus 0.9%NaCl and KCl plus 0.45%NaCl for correction of hypokalemia

  • OtherKCl plus 0.45%NaCl

    comparison of KCl plus 0.9%NaCl and KCl plus 0.45%NaCl for correction of hypokalemia

06

What researchers measure

Primary outcomes

  1. Number of participants with normal serum K as assessed by serum electrolyte

    Time frame: 24 hours

07

Study locations

1 of 1 sites recruiting
  • Phramonkutklao Hospital
    Bangkok, 10400, Thailand
    • Theerasak Tangwonglert, MD. · Contact · theerasak.pmk@gmail.com · 0897750222
    • Theerasak - Tangwonglert, MD. · Principal investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 3, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02721095
Lead sponsor
Phramongkutklao College of Medicine and Hospital
Responsible party
Sponsor
First posted
Mar 28, 2016
Start date
Aug 2014
Primary completion
Jul 2016 (estimated)
Completion
Sep 2016 (estimated)
Last update
May 3, 2016

Study contacts

Theerasak Tangwonglert, MD.
Contact
theerasak.pmk@gmail.com
0897750222
Yaowana Thanapat, MD
principal investigator · Instituitional review board royal thai army medical department

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2016. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion