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Status unknownNCT02720250Updated Mar 30, 2016

Omega-3 Fatty Acids Enriched Food and Microvascular Reactivity

An interventional study of Omega-3 chicken eggs and Regular chicken eggs in Omega-3 Polyunsaturated Fatty Acids, sponsored by Josip Juraj Strossmayer University of Osijek. Status unknown at 1 site in Croatia. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-03-30.

Sponsored by Josip Juraj Strossmayer University of Osijek · Not applicable and Interventional

The sponsor has not verified this record recently (last verified Mar 2016), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
18 Years to 35 Years
Sex
All
01

Study summary

Previous studies have shown that omega-3 fatty acid pills intake have beneficial effect on vascular health in overweight and/or hypertensive patients.

However, there is a lack of studies showing the effect of everyday consumption of omega-3 fatty acids enriched food (not pills) on lipid profile and microvascular reactivity in healthy population.

This study aimed to determine the effect of omega-3 enriched chicken eggs consumption on microvascular reactivity and lipid profile in young healthy subjects.

02

Conditions studied

  • Omega-3 Polyunsaturated Fatty Acids

Keywords

  • omega-3 fatty acids, microcirculation, laser Doppler flowmetry, lipid profile
03

In context

Lead sponsor

Josip Juraj Strossmayer University of Osijek is the lead sponsor of 26 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 35 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • healthy volunteers

Exclusion criteria

Exclusion Criteria:

  • oral contraceptives
  • drugs that could affect endothelium
  • hypertension
  • coronary artery disease
  • diabetes
  • hyperlipidaemia
  • renal impairment
  • cerebrovascular and peripheral artery disease
05

Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
50 participants (estimated)

Study arms

  • Experimental
    Omega-3

    Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks.

    Dietary Supplement: Omega-3 chicken eggs

  • Experimental
    Regular

    Intake of 3 regular chicken eggs per day for three weeks.

    Dietary Supplement: Regular chicken eggs

Interventions

  • Dietary supplementOmega-3 chicken eggs

    Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks.

  • Dietary supplementRegular chicken eggs

    Intake of 3 regular chicken eggs per day for three weeks.

06

What researchers measure

Primary outcomes

  1. microvascular reactivity

    Cutaneous microvascular blood flow will be measured by Laser Doppler Flowmetry in response to vascular occlusion (post occlusive reactive hyperaemia - PORH) and in response to iontophoresis of acetylcholine (ACh) (endothelium dependent vasodilation).

    Time frame: Three weeks

Secondary outcomes

  1. lipid profile

    Measurement of plasma cholesterol, HDL cholesterol, LDL cholesterol and triglycerides level.

    Time frame: Three weeks

07

Study locations

1 of 1 sites recruiting
  • Faculty of Medicine Osijek, Laboratory for Clinical and Sport Physiology
    Osijek, 31000, Croatia
    Recruiting
08

References and documents

Publications

  • Cavka A, Cosic A, Jukic I, Jelakovic B, Lombard JH, Phillips SA, Seric V, Mihaljevic I, Drenjancevic I. The role of cyclo-oxygenase-1 in high-salt diet-induced microvascular dysfunction in humans. J Physiol. 2015 Dec 15;593(24):5313-24. doi: 10.1113/JP271631. Epub 2015 Dec 7. PubMed 26498129 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 30, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02720250
Lead sponsor
Josip Juraj Strossmayer University of Osijek
Responsible party
Ines Drenjancevic (Vice Dean for Science, Faculty of Medicine Josip Juraj Strossmayer University of Osijek, Josip Juraj Strossmayer University of Osijek) — Principal investigator
First posted
Mar 25, 2016
Start date
Mar 2016
Primary completion
Dec 2017 (estimated)
Completion
Dec 2018 (estimated)
Last update
Mar 30, 2016

Study contacts

Ana Stupin, MD, PhD
Contact
anacavka@mefos.hr
+385915134958
Ines Drenjancevic, MD, PhD
Contact
ines.drenjancevic@mefos.hr
+385912241406
Ines Drenjancevic, MD, PhD
principal investigator · Faculty of Medicine, University of Osijek, Croatia

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2016. You cannot join it, but the record below documents what was studied.

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