An observational study in Cannabis Dependence, sponsored by University of Electronic Science and Technology of China. Completed at 1 site in Germany. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-02-02.
Sponsored by University of Electronic Science and Technology of China · Observational
The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a 28 supervised abstinence period. Previous research in cannabis users has predominantly focused on cognitive functions. Moreover, studies have implicated that observed deficits in cannabis users may regenerate after a prolonged abstinence period. Findings might provide important information with respect to relapse vulnerability.
517 studies on the registry are indexed under Marijuana Abuse; 114 are open to participants now.
This study's enrollment of 43 is below the median of 100 across 78 observational studies indexed under Marijuana Abuse.
Browse Marijuana Abuse studies →University of Electronic Science and Technology of China is the lead sponsor of 109 studies on the registry; 35 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Cannabis dependent individuals
Exclusion Criteria:
Cannabis dependent individuals according to DSM 4 criteria, aged 18-40 years
Other: fMRI
Healthy controls, socio-demographically matched
Other: fMRI
fMRI neural activation patterns of social-emotional brain processes after 28 day abstinence
Activity patterns in core regions of the emotion processing \& addiction-related brain networks (e.g. striatal regions, insular cortex, prefrontal cortex) will be assessed after 28-days of abstinence. Alterations will be determined by comparison with matched non-drug using controls
Time frame: one timepoint = fMRI assessment after 28 day abstinence period
Ratings of subjective experience (pleasantness, rewarding value) will be assessed after 28 days of abstinence
Self-reported ratings of pleasantness \& rewarding value during soft-pleasant touch.
Time frame: one timepoint = during fMRI assessment after 28 day abstinence period
Relapse interview assessed with Timeline-Followback Method
Association between fMRI neural correlates and drug use during follow up period as predictor of relapse
Time frame: one timepoint = 24 months post-fMRI-session
This study is completed, as verified in Feb 2017. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of Electronic Science and Technology of China