CClinicalTrials.gg
Status unknownNCT02664480Updated Jan 27, 2016

Assesment of Salivary Alpha-amylase Levels Before and After Ovulation

An observational study in Salivary Amylase, sponsored by Saglik Bilimleri Universitesi Gulhane Tip Fakultesi. Status unknown. Open to female participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-01-27.

Sponsored by Saglik Bilimleri Universitesi Gulhane Tip Fakultesi · Observational

The sponsor has not verified this record recently (last verified Jan 2016), so the status shown — last known as Enrolling by invitation — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
100
Ages
18 Years to 40 Years
Sex
Female
01

Study summary

Investigators aimed to investigate whether there is an association between ovulation and salivatory alpha amylase (sAA) activity in menstrual cycles during a month period in a group of reproductive women.

Read the detailed description

Saliva is a readily available specimen, which can be collected by noninvasive procedures and contains many hormones, drugs and antibodies of interest in screening and diagnosis. With a salivary specimen, one can collect multiple specimens at the optimum times for diagnostic information. Saliva can be collected in remote sites by unskilled personnel and, is stable at ambient temperatures for several weeks. Because of diurnal and monthly variations, several steroid hormones need multiple samples collected early in the morning or late at night or at the same time every day for a month to give meaningful results. Such collections are often very expensive, inconvenient or impossible to do with blood.

Investigators aimed to investigate whether there is an association between ovulation and salivatory alpha amylase (sAA) activity in menstrual cycles during a month period in a group of reproductive women.

02

Conditions studied

  • Salivary Amylase

Keywords

  • Salivary Alpha-amylase
  • ovulation
03

In context

Lead sponsor

Saglik Bilimleri Universitesi Gulhane Tip Fakultesi is the lead sponsor of 65 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Pcos women will included the study population. Because ovulation don't happen.

Inclusion criteria

  • Clinical diagnosis of PCOS (study group)
  • Reproductive age regular menses women

Exclusion criteria

Exclusion Criteria:

  • pregnancy,
  • breastfeeding,
  • known liver disease,
  • alcohol abuse,
  • diabetes mellitus,
  • smoking
  • treatment with oral glucocorticoids
  • treatment with hormonal contraceptives.
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
100 participants (actual)
Patient registry
No
Biospecimen retention
Samples without dna

Groups and cohorts

  • study group

    Reproductive age women with polycystic ovary syndrome and irregular menses (Salivary Alpha-amylase Levels of 3rd and 24th day of menstrual cyclus)

    Other: Salivary alpha-Amylases

  • control group

    Reproductive age women with regular menses (Salivary Alpha-amylase level of 3rd and 24th day of menstrual cyclus)

    Other: Salivary alpha-Amylases

Interventions

  • OtherSalivary alpha-Amylases

    Investigators will collect Salivary alpha-Amylases before and after ovulation

06

What researchers measure

Primary outcomes

  1. Changes of Salivary Alpha-amylase activity

    Saliva samples will be taken 2 times during the menstrual cyclus (3th day and 24th day).

    Time frame: 3rd and 24th day of menstrual cyclus

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 27, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02664480
Lead sponsor
Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Responsible party
Mustafa Ozturk (Etimesgut Military Hospital Obstetrics and Gynecology, Saglik Bilimleri Universitesi Gulhane Tip Fakultesi) — Principal investigator
First posted
Jan 27, 2016
Start date
Jan 2016
Primary completion
Feb 2016 (estimated)
Completion
Mar 2016 (estimated)
Last update
Jan 27, 2016

Study contacts

Mustafa Öztürk, M.D
principal investigator · Etimesgut Military Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2016. You cannot join it, but the record below documents what was studied.

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