CClinicalTrials.gg
TerminatedNCT02660476QUDOSUpdated Jun 22, 2023

Qatar Universal Diabetes Outcomes (QUDOS) Study

An observational study in Diabetes Mellitus and Type 2 Diabetes Mellitus, sponsored by Weill Cornell Medical College in Qatar. Terminated at 1 site in Qatar. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2023-06-22.

Sponsored by Weill Cornell Medical College in Qatar · Observational

Why this study was terminated
The study has been closed by our IRB due to the PI's departure from the Institution.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
475
Ages
18 Years to 70 Years
Sex
All
01

Study summary

QUDOS is a cross-sectional population study aiming to answer key questions about diabetes and its complications in Qatar as well as identify factors associated with the development and progression of diabetes complications.

Read the detailed description

QUDOS aims to gain a better understanding of diabetes in primary and secondary care over a period of 24 months.

A range of patients with diabetes will be sampled (including those with Type 1 diabetes as this group is under-studied in Qatar). This will be important in designing appropriate intervention plans that will improve diabetic patients' health conditions to prevent or delay the onset of complications and will provide a strong foundation for longitudinal study.

The broad objectives of the study are:

QUDOS 1: Aims to recruit 1,700 diabetic patients (including 200 with type 1 diabetes mellitus (independent of healthcare setting)) attending the hospitals and primary care and to collect the following data:

  • Demographics: age, sex, ethnicity, socio-economic background, smoking status;
  • Anthropometrics: vital signs, height, weight, body fat percentage, fat mass, neck and waist circumference;
  • Medical History: medications, complications, comorbidities, latest HbA1c and lipid profiles and family medical history;
  • Routine laboratory data;
  • Lifestyle: diet, physical activity,;
  • Sleep: quality and daytime sleepiness;
  • Cognition and Mental Health: depression, anxiety, stress and memory;
  • Diabetes microvascular complications: diabetic neuropathy, urine albumin/creatinine ratio; routine retinal screening data.
  • Gut microbiome from a stool sample

QUDOS 2: To further characterise 500 patients, from the total 1500 patients with T2DM recruited in QUDOS 1, who accept to continue with QUDOS 2 (a more detailed study and assessment).

This phase aims to concentrate on the following aspects:

  • Obstructive sleep apnoea;
  • Sleep duration and quality;
  • Diet;
  • Objective physical activity;
  • Stress;
  • Quality of Life;
  • Depression and anxiety;
  • Perceived control of health;
  • Detailed neuropathy screening;
  • Cardiovascular function;
  • Cognitive function;
  • Biological samples.
02

Conditions studied

  • Diabetes Mellitus
  • Type 2 Diabetes Mellitus

Keywords

  • Diet
  • Middle East and North Africa country
  • Health
  • Complication
  • Cardiovascular disease
  • Obesity
  • Stress
  • Obstructive Sleep Apnoea (OSA)
03

In context

Diabetes Mellitus

10,925 studies on the registry are indexed under Diabetes Mellitus; 1,318 are open to participants now.

This study's enrollment of 475 is above the median of 233 across 2,218 observational studies indexed under Diabetes Mellitus.

Browse Diabetes Mellitus studies →

Lead sponsor

Weill Cornell Medical College in Qatar is the lead sponsor of 12 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Adult patients 18-70 years old with diabetes, who are a resident in Qatar or born in one of the MENA countries with family originating from MENA countries, will be recruited from one of the following sites:

  • Primary health care centers
  • Hamad General Hospital
  • Al-Wakra Hospital
  • Al-Khor Hospital

Inclusion criteria

  1. Type 1 and Type 2 diabetes mellitus;
  2. Male or Female;
  3. Resident in Qatar;
  4. MENA birthplace and family origin;
  5. 18-70 years old;
  6. Capable to give informed consent and complete the study.

Exclusion criteria

Exclusion Criteria:

  1. Known pregnancy or planning pregnancy during the duration of study; 2. Congenital disorders; 3. Terminal illness; 4. Enrolled in a clinical trial involving medication; 5. Uncontrolled mental illness preventing participation; 6. Those who have already experienced a definitive microvascular complication:

i. End-stage renal disease; ii. Major amputation; iii. Blindness.

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
475 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • QUDOS 1

    Aims to recruit 1,700 diabetic patients (including 200 with type 1 diabetes mellitus (independent of healthcare setting)) attending the hospitals and primary care

  • QUDOS 2

    To further characterise 500 patients, from the total 1500 patients with T2DM recruited in QUDOS 1, who accept to continue with QUDOS 2 (a more detailed study and assessment).

06

What researchers measure

Primary outcomes

  1. Diabetes Complications (Nephropathy, Neuropathy, Retinopathy)

    Our primary analyses will be conducted to explore the potential cross-sectional relationships amongst proposed factors related to type 2 diabetes complications

    Time frame: Baseline (Cross-Sectional)

Secondary outcomes

  1. Mental Health

    To assess the relationships between T2DM and depression through questionnaires

    Time frame: Baseline (Cross-Sectional)

  2. Sleep and sleep related breathing disorders

    To assess the relationships between T2DM and sleep disordered breathing, sleep duration and sleep quality through a home sleep study

    Time frame: Baseline (Cross-Sectional)

  3. Physical activity

    To assess the relationships between T2DM and physical activity using an Actiwatch

    Time frame: Baseline (Cross-Sectional)

07

Study locations

1 site
  • Weill Cornell Medicine Qatar
    Doha, Qatar
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 22, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02660476
Lead sponsor
Weill Cornell Medical College in Qatar
Collaborators
Hamad Medical Corporation
Responsible party
Sponsor
First posted
Jan 21, 2016
Start date
Oct 2014
Primary completion
Jun 1, 2023
Completion
Jun 1, 2023
Last update
Jun 22, 2023

Study contacts

Shahrad Taheri, PhD
principal investigator · Weill Cornell Medical College in Qatar

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Jun 2023. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion