An observational study in Pulmonary Embolism, sponsored by Maastricht University Medical Center. Completed at 1 site in Netherlands. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-10-05.
Sponsored by Maastricht University Medical Center · Observational
Computed tomographic pulmonary angiography (CTPA) is considered the gold standard for the diagnosis of pulmonary embolism (PE). PE is a potentially fatal disease in which a thrombus is lodged into a pulmonary artery blocking blood flow and potentially leading to respiratory distress, acute right cardiac failure or death. Therefore early and correct diagnosis is crucial.
The diagnostic and clinical value of CTPA has already been firmly substantiated. Unfortunately up to 7.3% of PE scans are still deemed to be non-diagnostic, for example due to insufficient contrast enhancement in the target arteries.
Therefore future research should focus on two important aspects of CT imaging. On the one hand optimal enhancement for the individual patient, on the other hand preventing additional risk of CT imaging - namely contrast induced nephropathy (CIN) and radiation risk. Thus the purpose of our study will be to optimize radiation dose settings (e.g. tube voltage, tube current) and CM application for the individual patient in CTPA.
753 studies on the registry are indexed under Pulmonary Embolism; 157 are open to participants now.
This study's enrollment of 235 is below the median of 370 across 332 observational studies indexed under Pulmonary Embolism.
Browse Pulmonary Embolism studies →Maastricht University Medical Center is the lead sponsor of 852 studies on the registry; 116 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Consecutive patients referred for CTPA with a clinical suspicion of pulmonary embolism will be included.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Image quality
Evaluation of subjective and objective image quality based on individualized CTPA protocols
Time frame: one year
Reduction of radiation dose
Effect of individualized tube voltage settings on radiation
Time frame: one year
This study is completed, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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