An interventional study of PRP and Placebo in Hip Osteoarthritis, sponsored by Satakunta Central Hospital. Status unknown at 1 site in Finland. Open to participants aged 60 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-04-19.
Sponsored by Satakunta Central Hospital · Not applicable, Interventional, and Treatment
Study purpose is to evaluate perioperative usefulness of Platelet-rich Plasma (PRP) in total hip arthroplasty (THA) surgery. The study is designed as a randomized double blinded study using saline as placebo. The measurement outcomes includes objective variables (MRI, dynamometer) as well as subjective measurements (Oxford Hip Score, Harris Hip Score).
Patients are assigned to two different groups, according to a randomization list. PRP (approximately 9ml from which 1ml is delivered to in-house laboratory for the measurement of platelet count) is obtained from venous blood and applied to m. gluteus medius during the closure of modified lateral approach (Hardinge).
Study participants are evaluated preoperatively by trained physiotherapist. After surgery, participants undergo clinical evaluation and imaged (MRI) at 3 and 12 months post-operative. In the same time points, strength, Harris Hip Score and Oxford Hip Score. At the end of the study, the nature of the injected substance is revealed to the patients.
628 studies on the registry are indexed under Osteoarthritis, Hip; 121 are open to participants now.
This study's planned enrollment of 80 is below the median of 90 across 450 interventional studies indexed under Osteoarthritis, Hip.
Browse Osteoarthritis, Hip studies →Satakunta Central Hospital is the lead sponsor of 5 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Platelet-rich plasma taken made from centrifuged venous blood.
Biological: PRP
Sodium chloride 0.9% used as placebo.
Other: Placebo
The decrease of T2 weighted signaling between PRP and placebo group
Quantitative method of tissue healing
Time frame: Change from 3 months at 12 months
Differences in Harris Hip Score points between PRP and placebo group
Quality method of post-operative healing
Time frame: Change from 3 months at 12 months
Comparison of hip abduction strengths between PRP and placebo group using dynamometer
Quantitive method of abduction strengths
Time frame: Change from 3 months at 12 months
This study is status unknown, as verified in Apr 2016. You cannot join it, but the record below documents what was studied.
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Satakunta Central Hospital