CClinicalTrials.gg
Status unknownNCT02587949Updated Aug 14, 2018

The Correlation Between Hair Cortisol Level of Acute Stroke or Its Long Term Disability.

An observational study in Cerebrovascular Stroke, sponsored by Bnai Zion Medical Center. Status unknown at 1 site in Israel. Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2018-08-14.

Sponsored by Bnai Zion Medical Center · Observational

The sponsor has not verified this record recently (last verified Aug 2018), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
30
Ages
40 Years to 80 Years
Sex
All
01

Study summary

In patients admitted to hospital with acute cerebrovascular stroke, we want to study the relationship between hair cortisol levels and biomarkers of inflammation and the clinical and radiological severity of the stroke and the degree of neurological disability being tested in three months and one year after.

Read the detailed description

The study will include patients hospitalized due to an acute cerebrovascular stroke. A number of 30 patients aged 40-70 will be included. Within 48 hours of the event, blood inflammatory biomarkers, and scalp hair sample for cortisol will be taken. All recruited patients will undergo full neurological examination and the severity of the stroke will be rated using NIHSS (National Institutes of Health Stroke Scale). 3 months and one year later neurological examination and rating of neurological disability will be determined using Rankin Scale.

02

Conditions studied

  • Cerebrovascular Stroke

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Keywords

  • acute cerebrovascular stroke
03

In context

Stroke

7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.

This study's planned enrollment of 30 is below the median of 160 across 1,692 observational studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Bnai Zion Medical Center is the lead sponsor of 102 studies on the registry; 13 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

  1. Patients aged 40-80.
  2. Acute cerebrovascular stroke (symptoms that began no more than 72 hours before)
  3. Rankin 0-1 before the event

Inclusion criteria

  1. Patients aged 40-80.
  2. Acute cerebrovascular stroke (symptoms that began no more than 72 hours before)
  3. Rankin 0-1 before the event

Exclusion criteria

Exclusion criteria:

  1. Suspicion or known Cushing's syndrome
  2. Known adrenal failure
  3. Chronic inflammatory disease
  4. Active malignancy
  5. Acute infectious disease within 4 months before enrollment
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
30 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Anti Tumor Necrosis Factor alpha

    single blood sample will be drawn to measure Anti Tumor Necrosis Factor alpha levels (pg/ml).

    Time frame: 24 months

  2. C-reactive protein levels

    single blood sample will be drawn to measure c-reactive protein levels (mcg/dl).

    Time frame: 24 months

  3. Hair Cortisol level

    single hair sample will be drawn to measure cortisol levels (mcg/dl)

    Time frame: 24 months

  4. INL-6

    single blood sample will be drawn to measure INL-6 levels.

    Time frame: 24 months

Secondary outcomes

  1. TSH

    single blood sample will be drawn to measure Thyroid-Stimulating Hormone (mcIU/ml).

    Time frame: 24 months

  2. FT4

    single blood sample will be drawn to measure Free Thyroxine (pmol/L) .

    Time frame: 24 months

  3. FT3

    single blood sample will be drawn to measure Free Triiodothyronine (pmol/L).

    Time frame: 24 months

  4. Cortisol

    single blood sample will be drawn to measure cortisol levels (mcg/dl).

    Time frame: 24 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 14, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02587949
Lead sponsor
Bnai Zion Medical Center
Responsible party
Sponsor
First posted
Oct 27, 2015
Start date
Nov 2015
Primary completion
Nov 2019 (estimated)
Completion
Nov 2019 (estimated)
Last update
Aug 14, 2018

Study contacts

Mira Koch
Contact
mira.koch@b-zion.org.il
97248359351
Michal Yeiches
Contact
yeiches@gmail.com
97248359484

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.

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