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CompletedNCT02579109Updated Oct 19, 2015

Multisensorial Information's Treatment in Autism Spectrum Disorder

An interventional study of memory test in Autism, sponsored by Centre Hospitalier Universitaire de Nice. Completed. Open to participants aged 7 Years to 13 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-10-19.

Sponsored by Centre Hospitalier Universitaire de Nice · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Non-randomized
Ages
7 Years to 13 Years
Sex
All
01

Study summary

Introduction:

Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors. There's also deficits in social cognition. When having a face-to-face conversation, a listener not only hears what a speaker is saying, but also sees the articulatory gestures that accompany those sounds. Speech signals needs then a multisensory processing. Impairments in multisensory perceptual binding may be particularly relevant in ASD, given that hallmark features of the disorder include difficulties in speech, communication, and social interactions.

Objectives:

The investigator suggest that atypical multisensory processing in ASD may have an impact on speech perception and social processing.

Aims:

Methods:

This pilot study measures free recall scores in 3 lists of words presentation after 30 minutes. In the first condition (CI) words are only listening. In the second condition (CII) words are associated with a picture of a mans face. In the third condition (CIII) words are associated with a video of a man speaking. Three lists are homogeneous form words characteristics (lexical frequency, emotional valence norm, imageability). Participants were 7- to 13-year-olds typically developing children (TD) (N = 19) and ASD children (N = 19).

The investigator would create some new tools for exploring the treatment of a social information. These tools should be the closest of a ecological social interaction.

02

Conditions studied

03

In context

Autistic Disorder

1,344 studies on the registry are indexed under Autistic Disorder; 334 are open to participants now.

This study's enrollment of 38 is below the median of 45 across 1,044 interventional studies indexed under Autistic Disorder.

Browse Autistic Disorder studies →

Lead sponsor

Centre Hospitalier Universitaire de Nice is the lead sponsor of 709 studies on the registry; 176 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
7 Years to 13 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Boy or girl,
  • 7 - 13 years,
  • Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS,
  • Upper total IQ or equal to 50, examination dating less than year before the inclusion,
  • French-speaking children,
  • Signature of the informed consent by the parents(relatives) and the child,
  • Membership to the Social Security.

Exclusion criteria

Exclusion Criteria:

  • Genetic, neurological or neurosensory pathologies,
  • Diagnosis of intrusive disorder(confusion) of the not specified development: TED our,
  • The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
38 participants (actual)

Study arms

  • Other
    autistic patient

    patient with autistic trouble

    Other: memory test

  • Other
    healthy volunteers

    healthy volunteers

    Other: memory test

Interventions

  • Othermemory test
06

What researchers measure

Primary outcomes

  1. rate of reminder after 30 minutes between the group autistic and the group witness( %)

    Comparison between the group autistic and the group witness of the difference enter the rate of reminder(abseiling) in 30 minutes of the words proposed in video and audio sequences.

    Time frame: 30 minutes

Secondary outcomes

  1. Difference of the scores of reminders words (%)

    Difference of the scores of reminders between the both group, immediately after procedure and 30 minutes after procedure

    Time frame: 30 minutes

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 19, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02579109
Lead sponsor
Centre Hospitalier Universitaire de Nice
Responsible party
Sponsor
First posted
Oct 19, 2015
Start date
Feb 2014
Primary completion
Feb 2014
Completion
Aug 2014
Last update
Oct 19, 2015

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2015. You cannot join it, but the record below documents what was studied.

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