Status unknownNCT02553057lapVentUpdated Sep 17, 2015

Low Tidal Volume for Lung Protection During Anesthesia of Laparoscopic Surgery in Trendlenburg Position

An interventional study of mechanical ventilation in Intraoperative Mechanical Ventilation, sponsored by AlRefaey Kandeel. Status unknown at 1 site in Egypt. Open to participants aged 20 Years to 50 Years. Per ClinicalTrials.gov, last updated 2015-09-17.

Sponsored by AlRefaey Kandeel · Not applicable, Interventional, and Prevention

The sponsor has not verified this record recently (last verified Sep 2015), so the status shown — last known as Not yet recruiting — may be out of date.

Phase: Not applicable
Study type: Interventional
Enrollment: 90
Allocation: Randomized
Ages: 20 Years to 50 Years
Sex: All

Study summary

Mechanical ventilation of patients undergoing laparoscopic surgery may induce lung injury. Since lung protective ventilation has been recommended during anesthesia to prevent ongoing lung injury, so in our study the investigators will compare three different lung protective strategies regarding their lung protective effect measured by the incidence of postoperative pulmonary complications, perioperative oxygenation and postoperative inflammatory mediator release.

Conditions studied

Intraoperative Mechanical Ventilation

In context

Lead sponsor

AlRefaey Kandeel is the lead sponsor of 6 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 20 Years to 50 Years
Sexes eligible: All
Accepts healthy volunteers: No

Inclusion criteria

all patients undergoing laparoscopic colorectal or gynaecologic surgery with expected time more than two hours

Exclusion criteria

Exclusion Criteria:

refusal, preoperative pulmonary disease

Study design

Phase: Not applicable
Primary purpose: Prevention
Allocation: Randomized
Intervention model: Parallel assignment
Masking: None (open label)
Enrollment: 90 participants (estimated)

Study arms

Active comparator
Group 1
mechanical ventilation with Tidal volume 4 ml/kg and PEEP 8-10 cm H2o
Device: mechanical ventilation
Active comparator
Group2
mechanical ventilation with Tidal volume 6 ml/kg and PEEP 8-10 cm H2o
Device: mechanical ventilation
Active comparator
Group 3
mechanical ventilation with Tidal volume 8 ml/kg and PEEP 8-10 cm H2o
Device: mechanical ventilation

Interventions

Devicemechanical ventilation

What researchers measure

Primary outcomes

postoperative pulmonary complications
Time frame: 1 week

Study locations

1 site

Mansoura university
Mansoura, Dkahleya, Egypt

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Sep 17, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT02553057
Lead sponsor: AlRefaey Kandeel
Responsible party: AlRefaey Kandeel (Dr, Mansoura University) — Sponsor-investigator
First posted: Sep 17, 2015
Start date: Oct 2015
Primary completion: Oct 2016 (estimated)
Completion: Dec 2016 (estimated)
Last update: Sep 17, 2015

Oversight

Data monitoring committee: Yes

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2015. You cannot join it, but the record below documents what was studied.

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