CClinicalTrials.gg
TerminatedNCT02551601Updated Aug 14, 2019

Subfoveal Choroidal Thickness in Thai Population

An observational study in Healthy, sponsored by Khon Kaen University. Terminated at 1 site in Thailand. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-08-14.

Sponsored by Khon Kaen University · Observational

Why this study was terminated
No new participants
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
150
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using spectral-domain optical coherence tomography with enhanced depth imaging technique.

Read the detailed description

Alteration of choroidal blood supply causes changes in choroidal thickness and results in choroidal abnormalities. These are usually associated with retinal diseases and leading to severe visual dysfunction. Choroidal thickness is therefore helpful in diagnosis and treatment for many chorioretinal conditions. With the advent of spectral domain optical coherence tomography and enhanced depth imaging technique, choroidal thickness has been investigated widely in normal eyes and various chorioretinal diseases including central serous chorioretinopathy (CSC), age-related macular degeneration (AMD), highly myopia and Vogt Koyanagi-Harada disease. Similar to retinal thickness, a normal baseline choroidal thickness might be used for interpretation. This value might be affected by several variables including age, gender and ethnicity. Although there were previous studies on subfoveal choroidal thickness in normal eyes from many countries, there has been no such study in Thailand. The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using SD-OCT and EDI technique.

02

Conditions studied

  • Healthy

Keywords

  • subfoveal choroidal thickness
  • optical coherence tomography
  • enhanced depth imaging
03

In context

Lead sponsor

Khon Kaen University is the lead sponsor of 160 studies on the registry; 24 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Healthy volunteers, age 18 years or above, no ocular diseases

Inclusion criteria

  • Age 18 years or above
  • Healthy subjects
  • No ocular diseases
  • Written informed consent form

Exclusion criteria

Exclusion Criteria:

  • patients with systemic diseases that may affect retinal or choroidal thickness including diabetes
  • patients with history of refractive surgeries, intraocular surgeries or retinal laser treatments
  • patients with history of macular, retinal, or optic nerve abnormalities
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
150 participants (actual)
Patient registry
No

Groups and cohorts

  • Healthy volunteers

    to measure the subfoveal choroidal thickness in healthy volunteers

    Other: measure subfoveal choroidal thickness

Interventions

  • Othermeasure subfoveal choroidal thickness

    measure subfoveal choroidal thickness using optical coherence tomography

06

What researchers measure

Primary outcomes

  1. subfoveal choroidal thickness

    Thickness of choroid at the foveal area

    Time frame: up to 4 months

07

Study locations

1 site
  • Eye outpatients department, Srinagarind Hospital, Khon Kaen University
    Khon Kaen, 40002, Thailand
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 14, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02551601
Lead sponsor
Khon Kaen University
Responsible party
Yosanan Yospaiboon (Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen University) — Principal investigator
First posted
Sep 16, 2015
Start date
Aug 2015
Primary completion
Aug 2018
Completion
Aug 2018
Last update
Aug 14, 2019

Study contacts

Yosanan Yospaiboon, MD
principal investigator · Department of Ophthalmology, Khon Kaen University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion