CompletedNCT02537262Updated Jan 15, 2019

Effect of Preoperative Oral Carbohydrates on Quality of Recovery in Laparoscopic Colorectal Surgery Patients

An interventional study of carbohydrate beverage and NPO(None Per Oral) in Colorectal Disease, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 85 Years. Per ClinicalTrials.gov, last updated 2019-01-15.

Sponsored by Yonsei University · Not applicable, Interventional, and Treatment

Phase: Not applicable
Study type: Interventional
Enrollment: 74
Allocation: Randomized
Ages: 20 Years to 85 Years
Sex: All

Study summary

Preoperative midnight NPO is a traditional method for preventing aspiration during general anesthesia. However, recent studies reported that drinking carbohydrate beverage, three hours prior the surgery helps reducing patients starving, uncomfortment, and fatigue without other complication. QOR 40 is developed for evaluating patients' recovery condition regarding physical, psychological, and social aspects. Enhanced Recovery After Surgery(ERAS) is a concept for reducing patients' hospital stay and helping recovery. Studies showed that drinking carbohydrate beverage made better recovery of bowel function and shorter hospital stay in colorectal surgeries. However, the effect of carbohydrate drink for laparoscopic surgery is not yet proved. Therefore, the investigators will show the effect of carbohydrate drinking through this study.

Conditions studied

Colorectal Disease

Keywords

carbohydrate
quality of recovery(QOR) 40
enhanced recovery after surgery(ERAS)

In context

Lead sponsor

Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 20 Years to 85 Years
Sexes eligible: All
Accepts healthy volunteers: No

Inclusion criteria

patients undergoing laparoscopic colorectal surgery,
20\~85 year-old patients

Exclusion criteria

Exclusion Criteria:

diabetes mellitus
Inability to consume clear fluids
GERD or gastrointestinal obstruction
Liver cirrhosis
corticosteroid treatment
ASA>4
starting surgery five and more hours after drinking carbohydrate beverage
pregnancy

Study design

Phase: Not applicable
Primary purpose: Treatment
Allocation: Randomized
Intervention model: Parallel assignment
Masking: Single (Care provider)
Enrollment: 74 participants (actual)

Study arms

Experimental
carbohydrate group
Dietary Supplement: carbohydrate beverage
Placebo comparator
NPO(None Per Oral) group
Dietary Supplement: NPO(None Per Oral)

Interventions

Dietary supplementcarbohydrate beverage
Carbohydrate group drinks carbohydrate beverage 400ml(9PM\~MN) the day before the surgery and 200ml three hours before the surgery.
Dietary supplementNPO(None Per Oral)
NPO group does not drink any water from the MN before the surgery.

What researchers measure

Primary outcomes

total score of a survey using Quality of Recovery 40
Time frame: 1 day

Secondary outcomes

amount of perioperative water intake
measure with ml
Time frame: 1 day
amount of perioperative urine output
measure with ml
Time frame: 1 day
time to bowel function recovery
Time frame: 1 day
hospital stay duration from operation to discharge
Time frame: 1 month

Study locations

1 site

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine
Seoul, 120-752, Korea, Republic of

References and documents

Publications

Myles PS, Hunt JO, Nightingale CE, Fletcher H, Beh T, Tanil D, Nagy A, Rubinstein A, Ponsford JL. Development and psychometric testing of a quality of recovery score after general anesthesia and surgery in adults. Anesth Analg. 1999 Jan;88(1):83-90. doi: 10.1097/00000539-199901000-00016. PubMed 9895071 ↗
Noblett SE, Watson DS, Huong H, Davison B, Hainsworth PJ, Horgan AF. Pre-operative oral carbohydrate loading in colorectal surgery: a randomized controlled trial. Colorectal Dis. 2006 Sep;8(7):563-9. doi: 10.1111/j.1463-1318.2006.00965.x. PubMed 16919107 ↗

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Jan 15, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT02537262
Lead sponsor: Yonsei University
Responsible party: Sponsor
First posted: Sep 1, 2015
Start date: Jul 27, 2015
Primary completion: Aug 25, 2017
Completion: Aug 25, 2017
Last update: Jan 15, 2019

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.

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