An interventional study of Positron Emission Tomography using [11C]diprenorphine in Body Dysmorphic Disorders and Anorexia, sponsored by Centre Hospitalier Universitaire de Saint Etienne. Completed at 3 sites in France. Open to female participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-10-29.
Sponsored by Centre Hospitalier Universitaire de Saint Etienne · Not applicable, Interventional, and Diagnostic
The place of opioid system in anorexia nervosa (AN) physiopathology is still unclear. Conflicting results were published on cerebral spinal fluid or peripheral levels in anorexia nervosa. However, no data have been reported on opioid cerebral activity. Diprenorphine is a ligand with non-selective binding to opiate receptors µ, κ and δ capable to assess the interaction between endogenous opioids and their receptors.
56 studies on the registry are indexed under Body Dysmorphic Disorders; 11 are open to participants now.
This study's enrollment of 53 is close to the median of 52 across 44 interventional studies indexed under Body Dysmorphic Disorders.
Browse Body Dysmorphic Disorders studies →Centre Hospitalier Universitaire de Saint Etienne is the lead sponsor of 597 studies on the registry; 127 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cerebral \[11C\]diprenorphine Binding Potential measured by Positron emission Tomography (PET)
Drug: Positron Emission Tomography using [11C]diprenorphine
Cerebral \[11C\]diprenorphine Binding Potential measured by Positron emission Tomography (PET)
Drug: Positron Emission Tomography using [11C]diprenorphine
Cerebral \[11C\]diprenorphine Binding Potential measured by Positron emission Tomography (PET)
Drug: Positron Emission Tomography using [11C]diprenorphine
PET using \[11C\]diprenorphine
Also known as: PET
[11C]diprenorphine binding potential
Value of \[11C\]diprenorphine binding potential (BP) in predefined brains regions \[11C\] diprenorphine BP will be evaluated by brain positron emission tomography
Time frame: week 2
Correlation [11C]diprenorphine binding potential
Correlation between \[11C\]diprenorphine binding potential and plasma endogenous opioid levels
Time frame: week 2
Correlation [11C]diprenorphine binding potential
Correlation between \[11C\]diprenorphine binding potential and psychometric score evaluating addictive behavior, reward and positive reinforcement
Time frame: week 2
Correlation [11C]diprenorphine binding potential
Correlation between \[11C\]diprenorphine binding potential and appetite regulating hormones
Time frame: week 2
Correlation [11C]diprenorphine binding potential
Correlation between \[11C\]diprenorphine binding potential and LH response during GnRH test
Time frame: week 2
Plan to share: No
This study is completed, as verified in Oct 2018. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Centre Hospitalier Universitaire de Saint Etienne →