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Status unknownNCT02484612Updated May 11, 2016

Exercise Intensity and Appetite in Adolescents

An interventional study of acute exercise in Pediatric Obesity, sponsored by Université Blaise Pascal, Clermont-Ferrand. Status unknown. Open to male participants aged 12 Years to 15 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-05-11.

Sponsored by Université Blaise Pascal, Clermont-Ferrand · Not applicable, Interventional, and Basic science

The sponsor has not verified this record recently (last verified May 2016), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
12 Years to 15 Years
Sex
Male
01

Study summary

Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings.

Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults.

The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.

Read the detailed description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations:

  • anthropometric measurements
  • Body composition assessed by dual energy x-ray absorptiometry
  • Maximal aerobic test

They will then randomly complete the following conditions:

  • CON: a control day without exercise;
  • HIE: an exercise day with an exercise set at 75% of the capacities
  • LIE: an exercise day with an exercise set at 40% of the capacities

The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted.

Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.

02

Conditions studied

  • Pediatric Obesity

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03

In context

Pediatric Obesity

1,117 studies on the registry are indexed under Pediatric Obesity; 189 are open to participants now.

This study's planned enrollment of 30 is below the median of 103 across 862 interventional studies indexed under Pediatric Obesity.

Browse Pediatric Obesity studies →

Lead sponsor

Université Blaise Pascal, Clermont-Ferrand is the lead sponsor of 4 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
12 Years to 15 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • 12 to 15 years old adolescents
  • Obese according to international values for BMI
  • Being registered to the national social security insurance
  • no eating disorders
  • no medications
  • metabolic disorders

Exclusion criteria

Exclusion Criteria:

  • metabolic disorders
  • food disorders
  • physical disability
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Factorial assignment
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Lean adolescents

    15 lean adolescents (BMI Under the national cut-offs for obesity), 12-15 years old, males, will be recruited

    Behavioral: acute exercise

  • Experimental
    Obese adolescents

    15 obese adolescents (BMI above the national cut-offs for obesity), 12-15 years old, males, will be recruited

    Behavioral: acute exercise

Interventions

  • Behavioralacute exercise
06

What researchers measure

Primary outcomes

  1. energy intake in kcal

    buffet meal

    Time frame: up to 2 months

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 11, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02484612
Lead sponsor
Université Blaise Pascal, Clermont-Ferrand
Responsible party
THIVEL David (PhD, As/Pr, Research scientist, Université Blaise Pascal, Clermont-Ferrand) — Principal investigator
First posted
Jun 29, 2015
Start date
Sep 2016
Primary completion
Dec 2017 (estimated)
Completion
Dec 2017 (estimated)
Last update
May 11, 2016

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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