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CompletedNCT02442882Updated Jul 11, 2017

The Acute Effect of Boxing on Balance, Neuropsychological, and Visual Functions

An observational study in Craniocerebral Trauma, sponsored by Boston Children's Hospital. Completed. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-07-11.

Sponsored by Boston Children's Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
61
Ages
18 Years to 40 Years
Sex
All
01

Study summary

Prior research has investigated the effect of repetitive head trauma as it relates to physiological and psychological function. Boxing is one particular sport which predisposes athletes to a large amount of head impacts. We plan to assess the effects of a boxing tournament on balance, neuropsychological, and visual functions.

Read the detailed description

This is a prospective, repeated measures cohort study, which is able to make within-subject (pre and post boxing tournament) comparisons on measures of physiologic and behavioral function.

We plan to enroll boxing athletes who are participating in a boxing tournament. Each individual will be assessed on the following tests: balance (dynamic and static balance), vestibular-ocular motor function, neuropsychological function, and symptoms. Additionally, each boxing match will be video recorded and the total number of head impacts they sustain will be documented.

  • In order to prospectively assess how a boxing tournament affects balance, neuropsychological, and visual functions from pre-tournament assessments to post-tournament assessments (Specific Aim 1), we plan to test all athletes before competition at the Pan-American games begins (pre-test) and after they have been eliminated from the tournament (post-test).
  • In order to measure the associations between the number of head blows sustained during a boxing tournament with balance, neuropsychological, visual, and symptom deficits, we will also use a video camera to record each match and count the total number of hits to the head.
02

Conditions studied

  • Craniocerebral Trauma

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Keywords

  • Brain Concussion
  • Balance
  • Locomotion
  • Mild Traumatic Brain Injury
03

In context

Craniocerebral Trauma

253 studies on the registry are indexed under Craniocerebral Trauma; 45 are open to participants now.

This study's enrollment of 61 is below the median of 180 across 108 observational studies indexed under Craniocerebral Trauma.

Browse Craniocerebral Trauma studies →

Lead sponsor

Boston Children's Hospital is the lead sponsor of 598 studies on the registry; 151 are open to participants now.

Of its 31 completed or terminated interventional studies of FDA-regulated products, 18 (58%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients will be recruited from those who are participating at a boxing tournament.

Inclusion criteria

  1. Participation in boxing at a pre-specified tournament
  2. Medically cleared to participate in the tournament, as determined by the attending medical staff

Exclusion criteria

Exclusion Criteria:

  1. Any pre-existing neurological disorder, including but not limited to stroke, intracranial hemorrhage, any movement disorder, and cerebral palsy.
  2. Any currently active psychiatric condition, including specifically major depression, bipolar disorder or schizophrenia. A history of a psychiatric condition but no ongoing psychiatric episode (e.g. not currently undergoing treatment for a major depressive episode) would not be an exclusion.
  3. Any unstable medical condition
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
61 participants (actual)
Patient registry
No

Groups and cohorts

  • Boxers

    Individuals who participate in a boxing tournament will be tested on balance, neuropsychological, and visual functions before and after the tournament.

06

What researchers measure

Primary outcomes

  1. Balance Control

    Pre-tournament and post-tournament assessment of balance

    Time frame: 1 week

Secondary outcomes

  1. Neuropsychological function

    Pre-tournament and post-tournament assessment of neuropsychological function

    Time frame: 1 week

  2. Visual function

    Pre-tournament and post-tournament assessment of visual function

    Time frame: 1 week

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Howell DR, Meehan WP 3rd, Loosemore MP, Cummiskey J, Grabner von Rosenberg JP, McDonagh D. Neurological tests improve after Olympic-style boxing bouts: a pretournament and post-tournament study in the 2016 Women's World Boxing Championships. Br J Sports Med. 2017 Sep;51(17):1279-1284. doi: 10.1136/bjsports-2016-097160. Epub 2017 May 13. PubMed 28501805 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 11, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02442882
Lead sponsor
Boston Children's Hospital
Responsible party
David R Howell (Post-Doctoral Research Fellow, Boston Children's Hospital) — Principal investigator
First posted
May 13, 2015
Start date
Jul 2016
Primary completion
Jul 1, 2017
Completion
Jul 1, 2017
Last update
Jul 11, 2017

Study contacts

William P Meehan III, MD
principal investigator · Boston Children's Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2017. You cannot join it, but the record below documents what was studied.

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