An interventional study of cyrolipolysis (CoolSculpting device) and subcision in Cellulite, sponsored by Northwestern University. Active, not recruiting at 1 site in United States. Open to female participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-01.
Sponsored by Northwestern University · Not applicable, Interventional, and Treatment
This is a prospective randomized controlled study comparing the efficacy of cryolipolysis versus a combination of cryolipolysis and surgical subcision for the treatment of cellulite. The treatment sites are both outer thighs. One outer thigh will be randomized to receive one treatment of cryolipolysis, while the contralateral thigh will be assigned to receive the combination cryolipolysis plus surgical subcision. A live rating by a blinded dermatologist will evaluate the treatment and control areas using a cellulite severity scale at week 0 (before treatment) and at the 3-month follow up visit.
71 studies on the registry are indexed under Cellulite; 3 are open to participants now.
This study's enrollment of 15 is below the median of 34 across 65 interventional studies indexed under Cellulite.
Browse Cellulite studies →Northwestern University is the lead sponsor of 1,423 studies on the registry; 198 are open to participants now.
Of its 105 completed or terminated interventional studies of FDA-regulated products, 78 (74%) have results posted.
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Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Procedure: cyrolipolysis (CoolSculpting device)
Procedure: cyrolipolysis (CoolSculpting device) · Procedure: subcision
Treatment will be a cold exposure for up to 120 minutes using the CoolSculpting device with a commercially available treatment setting.
The skin will be punctured using a subcision needle to cut the septa responsible for the skin depression after cryolipolysis.
Live rating by a blinded dermatologist using cellulite severity scale
The cellulite severity scale rates cellulite 1-5 as mild, 6-10 as moderate, and 11-15 as severe.
Time frame: Change from Baseline in cellulite severity scale at 3 months
The record gives a start of Aug 2015, a primary completion of May 2026 and a completion of Dec 2028. It does not say whether these dates are actual or estimated.
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This study is active, not recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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