An interventional study of Meditation Workshop in Early Life Adversity and Chronic Stress, sponsored by University of North Carolina, Chapel Hill. Completed at 1 site in United States. Open to participants aged 35 Years to 64 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-07-15.
Sponsored by University of North Carolina, Chapel Hill · Not applicable, Interventional, and Basic science
Growing up in a low-income household has been shown to increase risk for, and susceptibility to many illnesses.The purpose of the study is to test an affective intervention for reversing biological risk factors, as related to childhood adversity, in midlife.
Participants will be asked to make two lab visits; attend six weekly, 1-hour meditation classes; as well as complete brief online daily surveys for 11 weeks, five biweekly surveys, and two 30-minute surveys prior to each lab visit. During the lab visits, participants will have their psychophysiology monitored for heart rate, blood pressure, respiration, and pulse. Participants will also have their blood drawn.
All surveys and questionnaires inquire about participants' current demographics, family history, perceptions about life and well-being, physical health, and monetary choices.
University of North Carolina, Chapel Hill is the lead sponsor of 1,340 studies on the registry; 133 are open to participants now.
Of its 155 completed or terminated interventional studies of FDA-regulated products, 136 (88%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
A six-week formal meditation workshop for 1 hour per week.
Behavioral: Meditation Workshop
A six-week formal meditation workshop for 1 hour per week.
Behavioral: Meditation Workshop
Six weeks of formal instruction in Lovingkindness or Mindfulness meditation.
Change in meditation time (Self-reported meditation time recorded daily)
Self-reported meditation time recorded daily.
Time frame: Weeks 3, 4, 5, 6, 7, 8, 9 ,10, 11, 12
Leukocyte basal gene expression (evaluated through blood samples)
Gene expression evaluated through blood samples.
Time frame: Week 0, Week 12
Levels of mistrust (Self-report questionnaire measure of hostility using 9-item Cooke-Medley scale)
Self-report questionnaire measure of hostility using 9-item Cooke-Medley scale.
Time frame: Week 0, Week 12
Temporal Discounting (Monetary choice questionnaire to assess impulsive decision-making)
Monetary choice questionnaire to assess impulsive decision-making.
Time frame: Week 0, Week 12
Cardiac vagal tone (Respiration and echocardiogram measured with respiration band and 2-lead electrode placement)
Respiration and echocardiogram measured with respiration band and 2-lead electrode placement, respectively. Three-minute spontaneous breath followed by five minutes of paced breathing intervals.
Time frame: Week 0, Week 12
This study is completed, as verified in Jul 2016. You cannot join it, but the record below documents what was studied.
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University of North Carolina, Chapel Hill