An observational study in Hiatus Hernia, sponsored by University of Zurich. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-07-03.
Sponsored by University of Zurich · Observational
Retrospective analysis for HRM measurements using liquid swallows and a test meal for the presence of hiatal hernia. The investigators will correlate hernia descriptions with presence of acidic reflux and clinical complaints.
We will retrospectively analyze all patients referred to hour unit for high-resolution esophageal manometry. These patients have been tested using liquid swallows and a test meal. We will analyze the HRM measurements for presence of manometric signs of hiatal hernia and determine predictive factors for hernia presence. We will correlate hernia description versus presence of acid reflux, clinical complaints and HRM measurements.
86 studies on the registry are indexed under Hernia, Hiatal; 28 are open to participants now.
This study's enrollment of 380 is above the median of 107 across 28 observational studies indexed under Hernia, Hiatal.
Browse Hernia, Hiatal studies →University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients referred to hour unit for high resolution manometry (patients with dysphagia, reflux or other complaints)
Exclusion Criteria:
high resolution esophageal manometry using liquid and solid swallows and a test meal.
Effects of hernia type (consistent hernia, transient hernia and no hernia, as specified bellow) on reflux symptoms
Time frame: 1 months
Differences in hernia size between sitting and recumbent position as well as between liquid swallows, free drinking and test meal.
Time frame: 1 hour
Diagnostic accuracy for hernia diagnosis by HRM for sitting, and recumbent position, free drinking and test meal.
Time frame: 1 hour
Correlation of pH-impedance measurements (if available) with manometric and clinical data.
Time frame: 1 hour
Correlation of various measurements describing esophageal motility according to Chicago classification with type of hernia, clinical symptoms and pH-impedance measurements
Time frame: 1 hour
Correlation of hernia diagnosis and hernia size according to imaging exams (if available: CT scan, fluoroscopy) and endoscopy (if available) with hernia diagnosis by HRM
Time frame: 1 hour
Correlation of body measurements (body mass index, BMI, waist circumference) of patients with type of hernia, clinical symptoms and pH-impedance measurements
Time frame: 1 hour
Correlation of visceral sensitivity (determined by balloon inflation) with reflux symptoms
Time frame: 1 hour
Prediction of reflux symptoms using a model including hernia and esophageal peristalsis characteristics, visceral sensitivity (balloon inflation) and anthropometric measurements
Time frame: 1 hour
This study is completed, as verified in Jul 2018. You cannot join it, but the record below documents what was studied.
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University of Zurich