CClinicalTrials.gg
Status unknownNCT02387021Updated Mar 12, 2015

Continuous Adductor Canal Block for Total Knee Arthroplasty Analgesia

An interventional study of Continuous femoral nerve block and Continuous adductor canal block in Neuromuscular Blockade and Pain Management, sponsored by Institut Kassab d'Orthopédie. Status unknown. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2015-03-12.

Sponsored by Institut Kassab d'Orthopédie · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Mar 2015), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Randomized
Ages
18 Years to 90 Years
Sex
All
01

Study summary

The purpose of the study is to determine whether the association of sciatic nerve block to continuous adductor canal block is effective in the treatment of total knee arthroplasty post operative pain .

02

Conditions studied

  • Neuromuscular Blockade
  • Pain Management

Keywords

  • analgesia
  • nerve block
  • Total knee replacement
03

In context

Lead sponsor

Institut Kassab d'Orthopédie is the lead sponsor of 4 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 90 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Elective unilateral TKA,
  • Planned continuous spinal anesthesia ,
  • Ability to follow study protocol,
  • American Society of Anesthesiologists class 1 to 3.

Exclusion criteria

Exclusion Criteria:

  • Contraindication for neuraxial anesthetic,
  • Chronic opioid use (defined as daily or almost daily use of opioids for >3 months),
  • Hypersensitivity and/or allergies to any of the study medications,
  • Intraoperative use of volatile anesthetics,
  • Preexisting neuropathy on the operative limb,
  • Contraindications to a femoral, adductor canal or Tibial nerve block.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
80 participants (estimated)

Study arms

  • Active comparator
    Continous femoral nerve block

    Patients will receive ultrasound-guided (USG) continuous femoral nerve block with 20 ml ropivacaine 0.2% and USG Continuous adductor canal block with 20 ml of saline and USG infragluteal SNB with 20 ml of saline .

    Procedure: Continuous femoral nerve block · Procedure: Continuous adductor canal block · Procedure: infragluteal Sciatic nerve block · Drug: Ropivacaine 0.2% · Drug: Saline

  • Experimental
    Continuous adductor canal block

    Patients will receive ultrasound-guided continuous adductor canal block with 20 ml ropivacaine 0.2% and USG infragluteal SNB with 20 ml ropivacaine 0.2% and USG continuous FNB with 20 ml of saline .

    Procedure: Continuous femoral nerve block · Procedure: Continuous adductor canal block · Procedure: infragluteal Sciatic nerve block · Drug: Ropivacaine 0.2% · Drug: Saline

Interventions

  • ProcedureContinuous femoral nerve block
  • ProcedureContinuous adductor canal block
  • Procedureinfragluteal Sciatic nerve block
  • DrugRopivacaine 0.2%
  • DrugSaline
06

What researchers measure

Primary outcomes

  1. Total Opioid-consumption

    Cumulative opioid consumption : converting oral, intravenous, and patient-controlled analgesia PCA opioid to morphine equivalent

    Time frame: 8 hours postoperative

Secondary outcomes

  1. NRS pain score at rest

    NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale at rest.

    Time frame: 0,1,2,4,6,8,12,24 and 48 hours postoperative

  2. NRS pain score during movement

    NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale, during physiotherapy.

    Time frame: 0,1,2,4,6,8,12,24 and 48 hours postoperative

  3. NRS pain score after 10 meters of walk or maximum walked distance

    NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale after 10 meters walk (if enable after maximum walked distance).

    Time frame: 8, 24 and 48 hours postoperative

  4. Ability to walk

    The ability of the patient to stand up and walk 3 meters.

    Time frame: 8, 24 and 48 hours postoperative

  5. TUG Test

    The TUG test measures the time it takes a patient to stand up from a chair, walk a distance of 3 m, and return to the chair

    Time frame: 8, 24 and 48 hours postoperative

  6. The 10-m walk test

    time it takes the patient to walk a distance of 10 m as quickly as possible

    Time frame: 8, 24 and 48 hours postoperative

  7. patient satisfaction

    patient interviewed, using a scale of 0-10, 0 not satisfied and 10 being the most satisfied

    Time frame: 8, 24 and 48 hours postoperative

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Kim DH, Lin Y, Goytizolo EA, Kahn RL, Maalouf DB, Manohar A, Patt ML, Goon AK, Lee YY, Ma Y, Yadeau JT. Adductor canal block versus femoral nerve block for total knee arthroplasty: a prospective, randomized, controlled trial. Anesthesiology. 2014 Mar;120(3):540-50. doi: 10.1097/ALN.0000000000000119. PubMed 24401769 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 12, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02387021
Lead sponsor
Institut Kassab d'Orthopédie
Responsible party
Rais Karim (Dr, Institut Kassab d'Orthopédie) — Principal investigator
First posted
Mar 12, 2015
Start date
Mar 2015
Primary completion
Dec 2015 (estimated)
Completion
Dec 2015 (estimated)
Last update
Mar 12, 2015

Study contacts

Karim Raies, M.D
Contact
karim.raies@gmail.com
+21655208602

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2015. You cannot join it, but the record below documents what was studied.

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