An interventional study of Prepmate in HIV, sponsored by University of California, San Francisco. Completed at 1 site in United States. Open to male participants aged 18 Years to 29 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-10-26.
Sponsored by University of California, San Francisco · Not applicable, Interventional, and Prevention
To test the effectiveness of Prepmate, a novel multi-modal, technology-based intervention for pre-exposure prophylaxis (PrEP) adherence support among young men who have sex with men (MSM).
University of California, San Francisco is the lead sponsor of 2,132 studies on the registry; 375 are open to participants now.
Of its 262 completed or terminated interventional studies of FDA-regulated products, 196 (75%) have results posted.
Counted across the registry records on this site, refreshed daily.
Eligible to initiate PrEP
Meet any of the following risk criteria for the prior 6 months:
Exclusion Criteria:
Behavioral: Prepmate
A novel multi-modal, technology-based intervention for pre-exposure prophylaxis (PrEP) adherence support .
PrEP adherence among young MSM over time based on dried blood spot (DBS)
PrEP adherence during follow-up based on dried blood spot (DBS) concentrations.
Time frame: DBS measured through week 36
Change in PrEP knowledge assessed via computer-assisted self-interview (CASI)
Change in PrEP knowledge assessed via computer-assisted self-interview (CASI) at baseline and week 36 (or early termination)
Time frame: baseline and week 36
Change in risk behaviors administered via CASI
Change in self-reported sexual risk behavior administered via CASI
Time frame: baseline through week 36
Change in risk perception administered by CASI
Changes in risk perception during the study administered by CASI
Time frame: baseline through week 36
Acceptability of Prepmate as measured by an acceptability index collected via CASI
Acceptability of Prepmate as measured by an acceptability index collected via CASI at 9 months (or early termination).
Time frame: Month 9 (or early termination)
Perceptions of Prepmate provided via individual exit interviews
Qualitative feedback provided via individual exit interviews with a subset of participants one month after Prepmate termination. Interviews will be open-ended and will cover topics such as usability, acceptability, user-experience and effectiveness of the Prepmate intervention.
Time frame: Month 10
Patterns of use of Prepmate texting service over time as measured by responses to text messages.
Use patterns of Prepmate texting service over time as measured by responses to text messages.
Time frame: through week 36
The incidence of sexually-transmitted infection (STI) among all participants.
Incidence of a combination endpoint of gonorrhea, chlamydia, and/or syphilis.
Time frame: through week 36
The number of participants who acquire HIV
The number of HIV infections (2) The drug resistance profiles of breakthrough infections
Time frame: week 36
This study is completed, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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University of California, San Francisco