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CompletedNCT02358954VPIUpdated Jul 14, 2015

Vestibular Pain Interactions

An interventional study of Quantitative sensory testing and CHEPS in Healthy, sponsored by University of Zurich. Completed at 1 site in Switzerland. Open to male participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-07-14.

Sponsored by University of Zurich · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
26
Allocation
Non-randomized
Ages
18 Years to 60 Years
Sex
Male
01

Study summary

The goal is to establish the practical usefulness of vestibular stimulation for modulating pain perception and to describe the possible mechanisms that could underlie neural vestibular-somatosensory interactions.

02

Conditions studied

  • Healthy

Keywords

  • quantitative sensory testing
  • contact heat evoked potentials
  • vection stimulation
  • 3D-turntable
  • Volunteers
03

In context

Lead sponsor

University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • Weight: 50 - 100 kg
  • Height: 155 - 185 cm
  • Male subjects 18 years to 60 years of age
  • Sufficient command of German language
  • Written informed consent by the participant after information about the project
  • Without any known history of neurological disease (especially motor, somatosensory disorders, peripheral neuropathies).
  • Right-handedness

Exclusion criteria

Exclusion Criteria:

  1. Intellectually or mental impaired subjects
  2. Drug abuse
  3. Chronic alcohol consumption
  4. No use of marihuana 24h before measurements.
  5. No history of vestibular or auditory disorders.
  6. Diabetes mellitus
  7. Participants of other studies during study period and 30 days prior to study begin
  8. Any regular concomitant medication
  9. Abnormal QST parameters at the baseline measurement.
  10. Absent CHEPs-Potentials at the baseline measurement.
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
26 participants (actual)

Study arms

  • Experimental
    Vestibular Pain interactions

    Procedure: Quantitative sensory testing · Procedure: CHEPS · Procedure: 3D Turntable · Procedure: Vection stimulation

Interventions

  • ProcedureQuantitative sensory testing

    Measurement of warm and cold detection and pain thresholds

    Also known as: QST

  • ProcedureCHEPS

    Measurement of amplitude and latency of cortically evoked potentials

    Also known as: Contact heat evoked potentials

  • Procedure3D Turntable
  • ProcedureVection stimulation
06

What researchers measure

Primary outcomes

  1. Pain thresholds

    The change in heat or cold pain threshold after physical vestibular stimulation and vection stimulation

    Time frame: After study inclusion, Day1

07

Study locations

1 site
  • University hospital Zurich
    Zurich, CH-8091, Switzerland
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 14, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02358954
Lead sponsor
University of Zurich
Responsible party
Lucian Macrea (Lucian M Macrea, University of Zurich) — Principal investigator
First posted
Feb 9, 2015
Start date
Jan 2015
Primary completion
Jun 2015
Completion
Jun 2015
Last update
Jul 14, 2015

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jul 2015. You cannot join it, but the record below documents what was studied.

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