An interventional study of Beer (alcoholic) and Placebo (non-alcoholic beer) in Healthy, sponsored by University Hospital, Basel, Switzerland. Completed at 1 site in Switzerland. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-09-28.
Sponsored by University Hospital, Basel, Switzerland · Not applicable, Interventional, and Basic science
The present study aims to evaluate effects of beer (alcohol) on social cognition.
Alcohol is one of the most widely used recreational drugs and it is often used in social settings to enhance sociability. There are few data showing that acute alcohol consumption affects facial emotion recognition. However the acute effects of alcohol in social drinkers on different aspects of social cognition are largely unknown. In the present study, we will therefore evaluate effects of beer (alcohol) on social cognition. The study will include 60 subjects (30 male, 30 female) and use a placebo-controlled, crossover design with the two experimental conditions alcoholic beer (individually calculated amount aiming to achieve a blood-alcohol concentration of 0.4g/kg), and non-alcoholic beer (placebo). We primarily aim to evaluate whether beer (alcohol) affects the ability to correctly decode emotions in facial expressions using different facial emotion recognition Tasks. Additionally, appraisal of visual erotic stimuli following alcohol consumption will be evaluated. Subjective social and mood effects will be assessed using validated questionnaires. Blood samples will be collected to assess plasma levels of the "social hormone" oxytocin as well as blood alcohol levels to test possible associations with effects on emotional processing.
University Hospital, Basel, Switzerland is the lead sponsor of 968 studies on the registry; 191 are open to participants now.
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Exclusion Criteria:
Cross-over within-subjects design with all treatment conditions tested in the same subject. This design has two treatment conditions in the same subject.
Other: Beer (alcoholic) · Other: Placebo (non-alcoholic beer)
Cross-over within-subjects design with all treatment conditions tested in the same subject. This design has two treatment conditions in the same subject.
Other: Beer (alcoholic) · Other: Placebo (non-alcoholic beer)
Beer (individually calculated amount aiming to achieve a blood-alcohol-centration of 0.4g/kg)
Non-alcoholic beer serves as Placebo.
Effect of beer (alcohol) on emotion recognition
Time frame: 3 hours
Effect of beer (alcohol) on empathy and social behavior
Time frame: 3 hours
Subjective effects of beer (alcohol)
Time frame: 3 hours
Effect of beer (alcohol) on appraisal of visual erotic stimuli
Time frame: 3 hours
Effects of beer (alcohol) on plasma oxytocin
Time frame: 3 hours
Effect modulation by genetic polymorphisms
Time frame: 3 hours
This study is completed, as verified in Sep 2015. You cannot join it, but the record below documents what was studied.
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University Hospital, Basel, Switzerland