An interventional study of Attention Bias Modification and Neutral Training in Anxiety and Anxiety Disorders, sponsored by University of Pittsburgh. Completed at 1 site in United States. Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2018-03-08.
Sponsored by University of Pittsburgh · Not applicable, Interventional, and Treatment
This project seeks to identify neural mechanisms underlying the tendency for anxious individuals to pay more attention to threatening information than to other types of information. A computerized treatment designed to train individuals to reduce their attention towards threat will be tested, with a focus on understanding the aspects of brain function that predict response to the treatment. This work could ultimately lead to the ability to treat anxiety more effectively by directly targeting the aspects of brain function that are altered in a given patient.
4,868 studies on the registry are indexed under Anxiety Disorders; 1,390 are open to participants now.
This study's enrollment of 70 is below the median of 80 across 4,174 interventional studies indexed under Anxiety Disorders.
Browse Anxiety Disorders studies →University of Pittsburgh is the lead sponsor of 1,385 studies on the registry; 167 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 4 (50%) have results posted.
Counted across the registry records on this site, refreshed daily.
Participants will:
Exclusion Criteria:
Behavioral: Attention Bias Modification
Behavioral: Neutral Training
Excessive attention to threat is theorized to be a critical contributor to chronic anxiety symptoms and related negative health consequences. Attention Bias Modification, which directly targets this mechanism, is a highly cost-effective intervention with growing empirical support for its potential efficacy in clinically anxious populations.
A control version of computerized attention training.
CAPS--Hypervigilance item
Time frame: 1 month
Mood and Anxiety Symptoms Questionnaire
Time frame: 1 month
Mini International Neuropsychiatric Interview (MINI)
Time frame: 1 month
Attentional bias towards threat (Performance-based assessment of attentional bias towards threat based on reaction times and eye tracking)
Performance-based assessment of attentional bias towards threat based on reaction times and eye tracking
Time frame: immediate
Penn State Worry Questionnaire
Time frame: 1 month
Liebowitz Social Anxiety Scale
Time frame: 1 month
World Health Organization Disability Assessment Scale (WHODAS)
Time frame: 1 month
Speilberger State-Trait Anxiety Inventory
Time frame: 1 month
Beck Anxiety Inventory
Time frame: 1 month
Functional Magnetic Resonance Imaging
(collected post-treatment in subsample of active arm only)
Time frame: 1 month
Pupillometry
Time frame: 1 month
This study is completed, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.
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University of Pittsburgh