An interventional study of embryo culture in different single-step media in Infertility, sponsored by Eugonia. Completed at 1 site in Greece. Open to female participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-06-09.
Sponsored by Eugonia · Not applicable, Interventional, and Treatment
This prospective study with sibling oocytes will evaluate the efficiency of two commercial single-step media, namely Sage 1-step and Continuous Single Culture Medium (CSCM), in terms of embryo utilization rates, blastocyst formation rates, embryo quality and pregnancy rates. Embryos will be cultured continuously for up to 6 days under identical conditions.
2,506 studies on the registry are indexed under Infertility; 407 are open to participants now.
This study's enrollment of 43 is below the median of 120 across 1,698 interventional studies indexed under Infertility.
Browse Infertility studies →Eugonia is the lead sponsor of 16 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Embryo culture in different single-step media: Half of each patient's oocytes will be randomly allocated to be cultured in Sage 1-step medium for up to six days following oocyte retrieval.
Other: embryo culture in different single-step media
Embryo culture in different single-step media: Half of each patient's oocytes will be randomly allocated to be cultured in CSC medium for up to six days following oocyte retrieval.
Other: embryo culture in different single-step media
Half of each patient's oocytes will be randomly allocated to be cultured either in Sage 1-step medium (Origio) or in CSC medium (Irvine Scientific) for up to six days following oocyte retrieval.
Utilization rates
Utilization = embryos selected for transfer and cryopreservation
Time frame: 6 days post oocyte retrieval
Blastocyst formation
Number of blastocysts on day 5 post oocyte retrieval per fertilized oocytes
Time frame: 5 days post oocyte retrieval
Embryo quality on day 3
Time frame: 3 days post oocyte retrieval
blastocyst quality on day 5
Time frame: 5 days post oocyte retrieval
positive pregnancy test
Time frame: 15 days post oocyte retrieval
clinical pregnancy
presence of gestational sac with positive fetal heartbeat
Time frame: 7 weeks of gestation
This study is completed, as verified in Jun 2015. You cannot join it, but the record below documents what was studied.
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Eugonia