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CompletedNCT02245113Updated Sep 19, 2014

Effects of High Oleic Palm Olein, Virgin Olive Oil and Coconut Oil Diets on Markers Selected in Malaysian

An interventional study of diets in Overweight, sponsored by Malaysia Palm Oil Board. Completed at 1 site in Malaysia. Open to participants aged 20 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-09-19.

Sponsored by Malaysia Palm Oil Board · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
32
Allocation
Randomized
Ages
20 Years to 60 Years
Sex
All
01

Study summary

This study will be comparing human body responses by the effects of diets cooked with NoveLin, virgin olive oil and RBD coconut oil.

Read the detailed description

NoveLin has high content of monounsaturate fatty acids - oleic acid (C18:1) which is the predominant fatty acid and in this study NoveLin is used as cooking fat in compare with olive oil. Olive oil is the world's most commonly eaten monounsaturated oil which contains 55 - 83% oleic acid. Consumption of olive oil gives numerous health benefits on lowering total and LDL cholesterol, reducing LDL cholesterol's, lowering blood clotting factors, and lowering blood pressure. Coconut oil is the richest source of medium chain fatty acid and it has greater than 90% of saturated fatty acid with dominant fatty acid of lauric acid (C12:0). RBD coconut oil is used as positive control in this study.

02

Conditions studied

  • Overweight

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03

In context

Overweight

3,670 studies on the registry are indexed under Overweight; 850 are open to participants now.

This study's enrollment of 32 is below the median of 73 across 3,175 interventional studies indexed under Overweight.

Browse Overweight studies →

Lead sponsor

Malaysia Palm Oil Board is the lead sponsor of 24 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • males and females aged 20-60 years
  • BMI 23 - 27.5 kg/m2
  • free from any disease
  • not on any medication or treatment associated with reduction of CVD
  • non-smokers and non-heavy drinker or having smoking or alcoholic history
  • not pregnant or lactating
  • willing and able to comply

Exclusion criteria

Exclusion Criteria:

  • people on weight reduction therapy/program
  • people on cholesterol reduction medicatio
  • have one or more of the chronic diseases
  • people with blood clotting problem/ coagulopathy / deep vein thrombosis.
  • hypertensive persons (systolic pressure > 140 mmHg, diastolic pressure > 90 mmHg)
  • female who is pregnant
  • people travel to overseas during feeding.
05

Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Participant)
Enrollment
32 participants (actual)

Study arms

  • Experimental
    Test Fat P

    Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3.

    Other: diets

  • Experimental
    Test Fat Q

    Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3.

    Other: diets

  • Experimental
    Test Fat R

    Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3.

    Other: diets

Interventions

  • Otherdiets

    Feeding trial for 6 weeks (week 0 - baseline). The experimental diets are comprised of 30% kcal fat, 15% kcal protein and 55% kcal carbohydrate. Each of the test fat contributes to two-thirds of total dietary fat will be compared.

06

What researchers measure

Primary outcomes

  1. change in c-peptide level

    Time frame: week 0(baseline) and week 6

Secondary outcomes

  1. change in insulin resistance's markers

    Time frame: week 0(baseline) and week 6

  2. change in inflammatory markers

    Time frame: week 0(baseline) and week 6

  3. change in obesity markers

    Time frame: week 0(baseline) and week 6

  4. change in lipid profile

    Time frame: week 0(baseline) and week 6

  5. change in physical characteristic (eg. BMI, body weight)

    Time frame: week 0(baseline) and week 6

07

Study locations

1 site
  • MPOB
    Kajang, Selangor 43000, Malaysia
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 19, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02245113
Lead sponsor
Malaysia Palm Oil Board
Collaborators
Universiti Putra Malaysia, International Medical University
Responsible party
Sponsor
First posted
Sep 19, 2014
Start date
Dec 2013
Primary completion
Jun 2014
Completion
Jul 2014
Last update
Sep 19, 2014

Study contacts

Voon Phooi Tee, PhD
principal investigator · MPOB
Lee Sin Tien, BSc
principal investigator · UPM
Norhaizan Md Esa, PhD
principal investigator · UPM
Tony Ng Kock Wai, PhD
principal investigator · IMU
Verna Lee Kar Mun, PhD
principal investigator · IMU

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2014. You cannot join it, but the record below documents what was studied.

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