An interventional study of Endoscopic Clip in Colonic Polyps, sponsored by Professor Michael Bourke. Completed at 1 site in Australia. Open to participants aged 18 Years to 99 Years. Per ClinicalTrials.gov, last updated 2025-03-27.
Sponsored by Professor Michael Bourke · Not applicable, Interventional, and Prevention
Patients will be randomised to have endoscopic clips applied to the Endoscopic Mucosal Resection (EMR) site following complete removal of the lesion, or will not receive clips and proceed with standard of care.
The outlined literature suggests that colonic post EMR bleeding may be prevented by the use of prophylactic endoscopic clips. There has thus far been no prospective study to confirm this concept. The ideal way to prove the hypothesis is to conduct a randomised controlled trial to evaluated the use of prophylactic clip placement on the EMR resection defect, for the purpose of preventing delayed bleeding in colonic wide field EMR (lesions>20mm). Given the significantly increased rate of bleeding in the proximal colon, clip placement in this location may have the greatest benefit. If it is proven that such a prophylactic technique is effective and safe, it may lead to significantly decreased patient morbidity and health care resources associated with the management delayed bleeding.
318 studies on the registry are indexed under Colonic Polyps; 54 are open to participants now.
This study's enrollment of 230 is below the median of 270 across 215 interventional studies indexed under Colonic Polyps.
Browse Colonic Polyps studies →Professor Michael Bourke is the lead sponsor of 20 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants randomised to the arm will receive endoscopic clips to their defect following EMR.
Device: Endoscopic Clip
These participants will receive standard of care practice only.
Post-Procedural Bleeding
Clinically significant post colonic wide-field EMR bleeding (CSPEB)
Time frame: 14 days
Safety success
Safety - admission rates, adverse outcomes, deaths Rate of initial technical success Duration of procedure Recurrence rate
Time frame: 18 months
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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Professor Michael Bourke