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Status unknownNCT02150226Updated Aug 7, 2019

Y-TZP and In-mouth Low Thermal Degradation: A Prospective Clinical Study

An interventional study of Lava plus (3M) crowns and bridges in Zirconia Monolithic Dental Restorations: In-mouth Behaviour, LTD and Wear, sponsored by University of Liege. Status unknown at 1 site in Belgium. Per ClinicalTrials.gov, last updated 2019-08-07.

Sponsored by University of Liege · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Aug 2019), so the status shown — last known as Active, not recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
101
Allocation
Not applicable
Sex
All
01

Study summary

The objective of this work is to study in-mouth aging and LTD of monolithic zirconia restorations. Microstructural changes characteristic of LTD processes, wear, and clinical behaviour following standard parameters will be evaluated. Notably Raman spectroscopy and 3D laser surface analysis will be used, directly on the restorations, which will be removed at regular intervals.The working hypothesis is that LTD process is very slow at the scale at the lifespan of dental prostheses.

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Conditions studied

  • Zirconia Monolithic Dental Restorations: In-mouth Behaviour, LTD and Wear
03

In context

Lead sponsor

University of Liege is the lead sponsor of 242 studies on the registry; 46 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Full zirconia crowns in the posterior region (molar/premolar)
  • On teeth or implants
  • Single unit restorations cemented on natural teeth and implants (including screw-retained restorations if possible, but no internal connections)
  • Multi-unit restorations on implants
  • If nightguard: to be performed on the antagonist

Exclusion criteria

Exclusion Criteria:

  • Patients with removable prosthesis as an antagonist
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
101 participants (actual)

Study arms

  • Experimental
    Experimental: Zirconia monolithic crowns and bridges

    Evaluation of Lava Plus zirconia dental crowns and bridges

    Device: Lava plus (3M) crowns and bridges

Interventions

  • DeviceLava plus (3M) crowns and bridges

    Zirconia monolithic dental crowns and bridges evaluation

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What researchers measure

Primary outcomes

  1. in-mouth LTD of monolithic zirconia restorations on natural teeth and implants

    Time frame: up to 5 years

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Study locations

1 site
  • Institute of Dentistry University of Liege
    Liege, 4000, Belgium
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References and documents

Publications

  • Koenig V, Wulfman CP, Derbanne MA, Dupont NM, Le Goff SO, Tang ML, Seidel L, Dewael TY, Vanheusden AJ, Mainjot AK. Aging of monolithic zirconia dental prostheses: Protocol for a 5-year prospective clinical study using ex vivo analyses. Contemp Clin Trials Commun. 2016 Jun 17;4:25-32. doi: 10.1016/j.conctc.2016.06.001. eCollection 2016 Dec 15. PubMed 29736467 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 7, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02150226
Lead sponsor
University of Liege
Collaborators
DMG Paris Descartes
Responsible party
Mainjot Amélie (Doctor, University of Liege) — Principal investigator
First posted
May 29, 2014
Start date
Feb 2014
Primary completion
Apr 2016
Completion
Apr 2021 (estimated)
Last update
Aug 7, 2019

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.

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