An interventional study of Ovarian and endometrial samples in Endometriosis, Ovarian, sponsored by Al-Azhar University. Completed at 1 site in Egypt. Open to female participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2014-04-04.
Sponsored by Al-Azhar University · Not applicable, Interventional, and Diagnostic
Purpose of this study is to evaluate stem cell expression (SCE) in endometriotic (E) and non endometriotic ovarian and endometrial tissues.
This study was conducted on 40 women at Al-Azhar University Hospitals. They are divided into two equal groups, group 1 with ovarian endometrioma and group 2 with normal ovary. Ovarian and endometrial samples were evaluated by hematoxlin \& eosin for histopathology (HP) and of oct-4 for immunohistochemistry (IH) for SCE.
Evaluation of IH parameters revealed that the most important factors for evaluating SC were arranged as score ( Edessy Stem Cell Score=ESS).
901 studies on the registry are indexed under Endometriosis; 259 are open to participants now.
This study's enrollment of 80 is above the median of 64 across 525 interventional studies indexed under Endometriosis.
Browse Endometriosis studies →Al-Azhar University is the lead sponsor of 505 studies on the registry; 167 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Ovarian and endometrial samples
Procedure: Ovarian and endometrial samples
Ovarian and endometrial samples
Procedure: Ovarian and endometrial samples
Ovarian and endometrial samples were evaluated by hematoxlin \&eosin for histopathology (HP) and of oct-4 for immunohistochemistry (IH) for SCE
Edessy Stem Cell Score (ESS)
ESS * Intensity of stem cell marker: Negative to mild =0, Moderate =1, Strong =2 * Percentage of stained cells: 0 =0, 0-50%= 1, \>50-100% =2. * Focality : None =0, Focal =1, Diffuse= 2 * Distribution: None= 0, Epithelial or mesenchymal= 1, Epithelial and mesenchymal= 2. * Localization of positive stained cell: None=0, Cytoplasmic or nuclear =1, Cytoplasmic and nuclear= 2
Time frame: 1 week
This study is completed, as verified in Mar 2014. You cannot join it, but the record below documents what was studied.
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Al-Azhar University