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CompletedNCT02015689Updated Dec 19, 2013

Altruistically Framed Messages and Impact on Parents' Reported Willingness to Immunize Their Children

An interventional study of Benefits to Child and Benefits to Society in Parental Vaccine Intentions for Their Children, sponsored by Indiana University. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-12-19.

Sponsored by Indiana University · Not applicable, Interventional, and Health services research

Phase
Not applicable
Study type
Interventional
Enrollment
802
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to examine the impact of different message framing (i.e., communication strategies) on parents' intentions to vaccinate their infants for measles, mumps, and rubella. We hypothesize that information specifically emphasizing various benefits of MMR vaccination will have different impacts on parents' reported levels of intention.

Read the detailed description

The purpose of this study is to investigate attitudes concerning the Measles, Mumps, \& Rubella (MMR) vaccine among adult parents in the United States. Attitudes will be assessed via a web-based survey administered by Survey Sampling International (SSI). Project sample size is 1,000, all to be recruited by SSI. The survey will take no more than 20-30 minutes to complete. The survey questions and response options attached. With the exception of demographic questions (e.g., age, sex, race) at the end of the survey, questions will not be able to be "skipped" because 1) the survey questions primarily assess attitudes and beliefs, 2) the questions are not of a sensitive nature, 3) responses are anonymous, 4) respondents have indicated their desire and willingness to respond to surveys like this by virtue of their enrollment as an SSI panel member, 5) there is no pressure for respondents to complete the survey, 6) respondents may cease responding to the survey at any time after they begin.

Respondents will be asked to provide information about their children's ages and sex, as well as historical recall information about their past vaccine decisions for their child/children. All respondents will receive general information from the Centers for Disease Control and Prevention (CDC) regarding MMR and the MMR vaccine (taken from the CDC's Vaccine Information Sheet), followed by summarized information about MMR and the MMR vaccine. A quarter of respondents will receive only this information. The other three-quarters of respondents will also receive additional "benefit" information that either underscores: a) the MMR vaccine's benefit to the child who receives it, b) the MMR vaccine's benefits to society as a whole, or c) the MMR vaccine's benefit to both the child who receives it as well as to society as a whole. The purpose of this additional "benefit" information (which will randomly vary among respondents) is to compare people's attitudes when they're given this information about the MMR vaccine's benefit to people's attitudes when they receive the general information. This information is noted in the attached survey, and mimics the information that parents are typically given in clinic settings regarding MMR and the MMR vaccine. The purpose of this study is to systematically assess people's responses to this information, which is already offered in clinical settings and is publicly available via the CDC.

02

Conditions studied

  • Parental Vaccine Intentions for Their Children
03

In context

Lead sponsor

Indiana University is the lead sponsor of 958 studies on the registry; 200 are open to participants now.

Of its 142 completed or terminated interventional studies of FDA-regulated products, 112 (79%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All

Inclusion criteria

  • 18 years of age or older
  • fluent in English
  • parent or primary caregiver to at least 1 child 17 years of age or younger

Exclusion criteria

Exclusion Criteria:

  • not fluent in English
  • younger than 18 years of age
  • not a parent or primary caregiver to someone 17 years of age or younger
05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Factorial assignment
Masking
Single (Participant)
Enrollment
802 participants (actual)

Study arms

  • Experimental
    Benefits to Child

    CDC VIS + message emphasizing benefits of MMR vaccine to child

    Behavioral: Benefits to Child · Behavioral: CDC VIS

  • Active comparator
    CDC VIS

    CDC Vaccine Information Statement (VIS)

    Behavioral: CDC VIS

  • Experimental
    Benefits to Society

    CDC VIS + message emphasizing benefits of MMR vaccine to society

    Behavioral: Benefits to Society · Behavioral: CDC VIS

  • Experimental
    Benefits to Child and Society

    CDC VIS + message emphasizing benefits of MMR vaccine to both child and to society

    Behavioral: Benefits to Child and Society · Behavioral: CDC VIS

Interventions

  • BehavioralBenefits to Child

    CDC VIS + message emphasizing benefits to child of MMR vaccine

  • BehavioralBenefits to Society

    CDC VIS + message emphasizing benefits to society of MMR vaccine

  • BehavioralBenefits to Child and Society

    CDC VIS + message emphasizing benefits both to child and to society of MMR vaccine

  • BehavioralCDC VIS

    CDC Vaccine Information Statement (VIS)

06

What researchers measure

Primary outcomes

  1. Parental MMR Vaccine Intentions for Their Children

    Participants report their willingness to vaccinate their infant for measles, mumps, and rubella on an 11-point scale anchored at 0(not at all likely) and 100(extremely likely) per the following prompt: On the scale below, please indicate how likely you are to have your baby receive the MMR vaccine.

    Time frame: Outcome (MMR intention) is measured immediately after participant receives message; measurement is immediate (not longitudnal follow-up)

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Hendrix KS, Finnell SM, Zimet GD, Sturm LA, Lane KA, Downs SM. Vaccine message framing and parents' intent to immunize their infants for MMR. Pediatrics. 2014 Sep;134(3):e675-83. doi: 10.1542/peds.2013-4077. Epub 2014 Aug 18. PubMed 25136038 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 19, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02015689
Lead sponsor
Indiana University
Responsible party
Sponsor
First posted
Dec 19, 2013
Start date
May 2012
Primary completion
May 2012
Completion
May 2012
Last update
Dec 19, 2013

Study contacts

Kristin S Hendrix, PhD
principal investigator · Indiana University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2013. You cannot join it, but the record below documents what was studied.

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