An observational study in Leukemia, Myeloid, Acute and Leukemia, Lymphoblastic, Acute, sponsored by University of Rochester. Completed at 1 site in United States. Open to participants aged Up to 50 Years. Per ClinicalTrials.gov, last updated 2017-04-11.
Sponsored by University of Rochester · Observational
The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial Hospital (Rochester, New York, USA). This standard of care was implemented based upon an earlier randomized trial (BMC Blood Disorders. 2004 Dec 10;4(1):6) The comparator will be historical controls from the medical literature.
The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial Hospital (Rochester, New York, USA). This standard of care was implemented based upon an earlier randomized trial (BMC Blood Disorders. 2004 Dec 10;4(1):6) The comparator will be historical controls from the medical literature. Key outcomes will be treatment related mortality (deaths at 30, 60 and 100 days) and three year survival.
3,035 studies on the registry are indexed under Leukemia, Myeloid, Acute; 746 are open to participants now.
This study's enrollment of 100 is below the median of 120 across 323 observational studies indexed under Leukemia, Myeloid, Acute.
Browse Leukemia, Myeloid, Acute studies →University of Rochester is the lead sponsor of 728 studies on the registry; 115 are open to participants now.
Of its 56 completed or terminated interventional studies of FDA-regulated products, 44 (79%) have results posted.
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The study population is comprised of 98 men and women who were both diagnosed and treated for Acute Myeloid Leukemia or Acute Lymphoid Leukemia at Strong Memorial Hospital, a tertiary medical center located in Rochester, NY, USA. All of these patients received washed red cell and platelet transfusions as part of the hospital's standard protocol for patients with acute leukemia.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Survial Rate at 30 Days
The percentage of patients who were alive at 30 days after transfusion.
Time frame: 30 days
Survial Rate at 60 Days
The percentage of patients who were alive at 60 days after transfusion.
Time frame: 60 days
Survial Rate at 100 Days
The percentage of patients who were alive at 100 days after transfusion.
Time frame: 100 days
Survial Rate at 5 Years
The percentage of patients who were alive at 5 years after transfusion.
Time frame: 5 years
| Milestone | Washed | Unwashed |
|---|---|---|
| Started | 69 | 31 |
| Completed | 69 | 31 |
| Not completed | 0 | 0 |
The percentage of patients who were alive at 30 days after transfusion.
| percentage of participants | Washed | Unwashed |
|---|---|---|
| Survial Rate at 30 Days | 100 | 97 |
The percentage of patients who were alive at 60 days after transfusion.
| percentage of participants | Washed | Unwashed |
|---|---|---|
| Survial Rate at 60 Days | 97 | 94 |
The percentage of patients who were alive at 100 days after transfusion.
| percentage of participants | Washed | Unwashed |
|---|---|---|
| Survial Rate at 100 Days | 96 | 87 |
The percentage of patients who were alive at 5 years after transfusion.
| percentage of participants | Washed | Unwashed |
|---|---|---|
| Survial Rate at 5 Years | 55 | 39 |
Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Washed | — | — | — |
| Unwashed | — | — | — |
| Age, Continuous(years) | Washed | Unwashed | Total |
|---|---|---|---|
| Mean | 40 (1 to 50) | 30 (2 to 49) | 35 (1 to 50) |
| Sex: Female, Male(Participants) | Washed | Unwashed | Total |
|---|---|---|---|
| Female | 46 | 18 | 64 |
| Male | 23 | 13 | 36 |
| Region of Enrollment(participants) | Washed | Unwashed | Total |
|---|---|---|---|
| United States | 69 | 31 | 100 |
This study is completed, as verified in Apr 2017. You cannot join it, but the record below documents what was studied.
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