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CompletedNCT01971021Updated Jan 30, 2018

Vascular Access in Cancer Patients - PICC vs PORT in a Randomized Controlled Trial.

An interventional study of PICC or subcutaneous venous port in Focus of Study, sponsored by Linkoeping University. Completed at 1 site in Sweden. Open to participants aged 18 Years to 120 Years. Per ClinicalTrials.gov, last updated 2018-01-30.

Sponsored by Linkoeping University · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Registered 5 months after the study started (first participant enrolled Apr 2013, registered Sep 2013).
Phase
Not applicable
Study type
Interventional
Enrollment
400
Allocation
Randomized
Ages
18 Years to 120 Years
Sex
All
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Study summary

As of today there is very limited scientific knowledge in whicj of the two vascular access devices (PICC-line or venous ports) that offers the lowest complicationrates in cancerpatients. The study group wants to clearify this unsolved matter by comparing the two systems. Our primary endpoint is the presens of catheter related venous thrombosis. We are also looking at all catheter related complications and patient satisfaction.

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Conditions studied

  • Focus of Study
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In context

Lead sponsor

Linkoeping University is the lead sponsor of 189 studies on the registry; 40 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 120 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • cancer treatment with need for central venous access
  • Age >18 yrs
  • Suspected survival > 4 weeks
  • Need of central venous access >4 weeks

Exclusion criteria

Exclusion Criteria:

  • Ongoing uncontrolled systemic infection
  • Prescence of significant thrombosis/stenosis in arm or central veins
  • Unability to communicate
  • Probable upcoming need for dialysis fistula
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Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
400 participants (actual)

Study arms

  • Active comparator
    PICC-line

    PICC line insertion.

    Device: PICC or subcutaneous venous port

  • Active comparator
    PORT

    Subcutaneous venous port insertion

    Device: PICC or subcutaneous venous port

Interventions

  • DevicePICC or subcutaneous venous port
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What researchers measure

Primary outcomes

  1. The occurence of catheter related venous thrombosis

    regular follow-ups at month 1, 3, 6 and 12.

    Time frame: Upon clinical suspiscion during the one the patient i enrolled in the study

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Study locations

1 site
  • Dept of Oncology
    Jönköping, 551 11, Sweden
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References and documents

Publications

  • Taxbro K, Hammarskjold F, Juhlin D, Hagman H, Bernfort L, Berg S. Cost analysis comparison between peripherally inserted central catheters and implanted chest ports in patients with cancer-A health economic evaluation of the PICCPORT trial. Acta Anaesthesiol Scand. 2020 Mar;64(3):385-393. doi: 10.1111/aas.13505. Epub 2019 Nov 27. PubMed 31721153 ↗
  • Taxbro K, Hammarskjold F, Thelin B, Lewin F, Hagman H, Hanberger H, Berg S. Clinical impact of peripherally inserted central catheters vs implanted port catheters in patients with cancer: an open-label, randomised, two-centre trial. Br J Anaesth. 2019 Jun;122(6):734-741. doi: 10.1016/j.bja.2019.01.038. Epub 2019 Apr 17. PubMed 31005243 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01971021
Lead sponsor
Linkoeping University
Collaborators
Ryhov County Hospital
Responsible party
Knut Taxbro (MD Consultant in Anesthesia and Intensive Care, Linkoeping University) — Principal investigator
First posted
Oct 28, 2013
Start date
Apr 2013
Primary completion
Jan 29, 2018
Last update
Jan 30, 2018

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.

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