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CompletedNCT01925833Updated Feb 12, 2019

Adenoma Detection by Polypectomy During Both Insertion and Withdrawal

An interventional study of Both insertion and withdrawal and Only withdrawal in Adenoma of Large Intestine, sponsored by The Catholic University of Korea. Completed. Open to participants aged 50 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-02-12.

Sponsored by The Catholic University of Korea · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
1,142
Allocation
Randomized
Ages
50 Years to 80 Years
Sex
All
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Study summary

Standard method of colonoscopy is to insert the colonoscope rapidly to reach the cecum, with careful inspection and polypectomy during the withdrawal phase. However, small polyps (e.g. \<1cm) seen during insertion phase are difficult to find during withdrawal phase. Also, colon is in different conformation during insertion and withdrawal phases. We think careful inspection and polypectomy during both insertion and withdrawal can improve adenoma detection rate.

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Conditions studied

  • Adenoma of Large Intestine
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In context

Lead sponsor

The Catholic University of Korea is the lead sponsor of 155 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
50 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patient undergoing screening or surveillance colonoscopy

Exclusion criteria

Exclusion Criteria:

  • Previous colorectal resection, Polyposis syndrome, Inflammatory bowel disease
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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
1,142 participants (actual)

Study arms

  • Experimental
    Both insertion and withdrawal

    Procedure: Both insertion and withdrawal

  • Active comparator
    Only withdrawal

    Procedure: Only withdrawal

Interventions

  • ProcedureBoth insertion and withdrawal

    inspection and polypectomy during both insertion and withdrawal of colonoscopy

  • ProcedureOnly withdrawal

    inspection and polypectomy during only withdrawal of colonoscopy

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What researchers measure

Primary outcomes

  1. Adenoma detection rate

    Time frame: 4 weeks

Secondary outcomes

  1. Number of adenoma per patient

    Time frame: 4 weeks

Other outcomes

  1. Polyp miss rate

    Time frame: 4 weeks

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Gweon TG, Lee SW, Ji JS, Lee JR, Kim JS, Kim BW, Choi H. Comparison of adenoma detection by colonoscopy between polypectomy performed during both insertion and withdrawal versus during withdrawal only: a multicenter, randomized, controlled trial. Surg Endosc. 2020 Dec;34(12):5461-5468. doi: 10.1007/s00464-019-07342-4. Epub 2020 Jan 17. PubMed 31953727 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 12, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01925833
Responsible party
Jeong-Seon Ji (Dr, The Catholic University of Korea) — Principal investigator
First posted
Aug 20, 2013
Start date
Sep 2013
Primary completion
Jul 2016
Completion
Dec 2016
Last update
Feb 12, 2019

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.

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