An interventional study of Dexmedetomidine and saline in Steep Trendelenburg Position With Penumoperitoneum in Robot Assisted Laparoscopic Prostatectomy, sponsored by Yonsei University. Completed. Open to male participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2014-01-27.
Sponsored by Yonsei University · Not applicable, Interventional, and Supportive care
Intraocular pressure is significantly increase during robot-assisted laparoscopic radical prostatectomy which is performed in a steep trendelenburg position at prolonged timeds of pneumoperitoneum. Threrefore we decided to evaluate the effect of dexmedetomidine in intraocular pressure during roboti-assisted laparoscopic radical prostatectomy.
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dexmedetomidine infusion from beginning of the anesthesia to just before returning to horizontal position
Drug: Dexmedetomidine
Saline infusion from same time period.
Drug: saline
Influence of dexmedetomidine in intraocular pressure during robot-assisted laparoscopic prostatectomy.
T0: Pre-induciton T1: 5min after anesthesia induction T2: 5 min after establish pneumoperitoneum T3: 15min after steep trendelenburg position T4: 30min after steep trendelenburg position T5: 45min after steep trendelenburg T6: 60min after steep trendelenburg T7: 75min after steep trendelenburg T8: 5min after returning to horizontal position T9: operation end T10: 5min after tracheal extubation T11: 60min after tracheal extubation
Time frame: change of intraocular pressure from T0 to T11 for 60mins
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Yonsei University