CClinicalTrials.gg
Status unknownNCT01860469Updated May 22, 2013

Reducing Mesh Infections in Open Hernia Repairs

A Phase 2/3 interventional study of vancomycin-soaked mesh and plain mesh in Patients Undergoing Open Hernia Repair and Patients Undergoing Ventral or Inguinal Hernia Repair, sponsored by University of Saskatchewan. Status unknown at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-05-22.

Sponsored by University of Saskatchewan · Phase 2/3, Interventional, and Prevention

The sponsor has not verified this record recently (last verified May 2013), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Phase 2/3
Study type
Interventional
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Soaking meshes in a vancomycin solution just prior to their use in open hernia repairs will decrease rates of mesh infection

02

Conditions studied

  • Patients Undergoing Open Hernia Repair
  • Patients Undergoing Ventral or Inguinal Hernia Repair
03

In context

Hernia

1,096 studies on the registry are indexed under Hernia; 132 are open to participants now.

Browse Hernia studies →

Lead sponsor

University of Saskatchewan is the lead sponsor of 237 studies on the registry; 33 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • open ventral or inguinal hernia repair

Exclusion criteria

Exclusion Criteria:

  • laparoscopic hernia repair
  • non ventral or inguinal hernia repairs
05

Study design

Phase
Phase 2 / Phase 3
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single

Study arms

  • Active comparator
    plain mesh

    standard practice of using plain mesh (non vancomycin-soaked) for open hernia repair

    Procedure: plain mesh

  • Experimental
    vancomycin-soaked mesh

    use of vancomycin-soaked mesh for open hernia repair

    Procedure: vancomycin-soaked mesh

Interventions

  • Procedurevancomycin-soaked mesh
  • Procedureplain mesh

    Also known as: non vancomycin-soaked mesh

06

What researchers measure

Primary outcomes

  1. mesh infections

    Time frame: 6 months

Secondary outcomes

  1. hernia recurrence

    Time frame: 6 months

  2. postoperative seroma formation

    Time frame: 6 months

07

Study locations

1 site
  • Five Hills Health Region
    Moose Jaw, Saskatchewan S6H 1H3, Canada
    • Ali Cadili, MD, FRCSC · Contact · alicadili1@gmail.com · 3066940200
    • Ali Cadili, MD, FRCSc · Principal investigator
    • Nishaan Cheddie, MD, FRCSc · Sub investigator
    • George B Miller, MD, FRCSc · Sub investigator
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 22, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01860469
Lead sponsor
University of Saskatchewan
Responsible party
Ali Cadili (Clinical Assistant Professor, University of Saskatchewan) — Principal investigator
First posted
May 22, 2013
Start date
Jun 2013
Primary completion
Jun 2014 (estimated)
Last update
May 22, 2013

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2013. You cannot join it, but the record below documents what was studied.

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