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CompletedNCT01843153Updated Mar 31, 2015

Continuous Versus Intermittent Sciatic Block for Total Knee Arthroplasty

A Phase 4 interventional study of Ropivacaine in Total Knee Arthroplasty and Pain, sponsored by Kreiskrankenhaus Dormagen. Completed at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-03-31.

Sponsored by Kreiskrankenhaus Dormagen · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
140
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The role of a sciatic block in addition to a femoral block remains controversial. The study addresses this topic by comparing a continuous block versus an injection on demand.

02

Conditions studied

  • Total Knee Arthroplasty
  • Pain

Keywords

  • pain score
03

In context

Lead sponsor

Kreiskrankenhaus Dormagen is the lead sponsor of 6 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients scheduled for total knee arthroplasty

Exclusion criteria

Exclusion Criteria:

  • failure to establish femoral and sciatic block
  • insufficient analgesic effect of the block
  • patient declines to participate
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
140 participants (actual)

Study arms

  • Other
    intermittent

    injection of ropivacaine on demand

    Drug: Ropivacaine

  • Other
    continuous

    continuous ropivacaine infusion

    Drug: Ropivacaine

Interventions

  • DrugRopivacaine
06

What researchers measure

Primary outcomes

  1. pain score (VRS)

    Time frame: 4 days

Secondary outcomes

  1. frequency of injections into the sciatic catheter

    Time frame: 4 days

07

Study locations

1 site
  • KKH Dormagen
    Dormagen, D-51375, Germany
08

References and documents

Publications

  • Soltesz S, Meiger D, Milles-Thieme S, Saxler G, Ziegeler S. Intermittent versus continuous sciatic block combined with femoral block for patients undergoing knee arthroplasty. A randomized controlled trial. Int Orthop. 2016 Sep;40(9):1861-7. doi: 10.1007/s00264-016-3117-3. Epub 2016 Jan 25. PubMed 26810904 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 31, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01843153
Lead sponsor
Kreiskrankenhaus Dormagen
Responsible party
Sponsor
First posted
Apr 30, 2013
Start date
Apr 2013
Primary completion
Oct 2014
Completion
Dec 2014
Last update
Mar 31, 2015

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2013. You cannot join it, but the record below documents what was studied.

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