An observational study in Venous Thromboembolism, sponsored by HaEmek Medical Center, Israel. Completed at 1 site in Israel. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-12-16.
Sponsored by HaEmek Medical Center, Israel · Observational
Can thrombin generation measurement predict the risk of venous thromboembolism in acute ill patients
Traditional coagulation tests do not assess the whole coagulation system. Thrombin generation assays measure the ability of plasma sample to generate thrombin following in vitro activation of coagulation. In contrast to the classical clotting assays, thrombin generation reflects and integrates all pro and anticoagulant reactions that regulate the formation and inhibition of thrombin.
The aim of our study is to investigate whether thrombin generation would be able to predict a hypercoagulable state in acute ill patients admitted in the internal medical departments and how it correlates with the Padua prediction score, a score that could assists the risk for venous thromboembolism in hospitalized medical patients.
In total 300 patients are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant. We will measure the thrombin generation over time in plasma assessed by the calibrated automated thrombogram (CAT).
818 studies on the registry are indexed under Thromboembolism; 98 are open to participants now.
This study's enrollment of 400 is below the median of 500 across 344 observational studies indexed under Thromboembolism.
Browse Thromboembolism studies →HaEmek Medical Center, Israel is the lead sponsor of 228 studies on the registry; 12 are open to participants now.
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300 hospitalized patients
Exclusion Criteria:
venous thromboembolism
Time frame: 1 week
This study is completed, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.
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HaEmek Medical Center, Israel