CClinicalTrials.gg
CompletedNCT01740661Updated Apr 16, 2014

Cryotherapy and Joint Biomechanics During Running

An interventional study of Cryotherapy and Control in Musculoskeletal Injury, sponsored by University of Calgary. Completed at 1 site in Canada. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-04-16.

Sponsored by University of Calgary · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
26
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
All
01

Study summary

The purpose of this study is to determine the immediate effects of cryotherapy on the lower extremity biomechanics during running.

Read the detailed description

Cryotherapy or cold therapy has widely been used as a treatment modality in both acute and chronic injuries. It is believe that the application of cryotherapy can help to decrease pain, muscle soreness, soft tissue swelling, and cause vasoconstriction of blood vessels reducing heat loss. The nerve conduction velocity and muscle-spindle firing rate also decreases with cryotherapy, which results in changes in proprioception acuity. Cryotherapy has also been used prior to exercise (pre-cooling) to improve endurance activities. However, given the possible detrimental effects of cryotherapy on proprioception acuity, the use of this treatment modality prior to exercise could pose an increased risk of musculoskeletal injury. The effects of cryotherapy on lower extremity biomechanics during athletic movements is poorly understood despite the wide use among physiotherapists, athletic therapists and clinicians. Therefore, the purpose of this investigation is to determine the effects of cold water immersion on lower extremity biomechanics during running. The investigators hypothesize that cryotherapy as a form of treatment can increase the load in the lower extremity joint during gait biomechanics.

02

Conditions studied

  • Musculoskeletal Injury
03

In context

Lead sponsor

University of Calgary is the lead sponsor of 686 studies on the registry; 189 are open to participants now.

Of its 10 completed or terminated interventional studies of FDA-regulated products, 2 (20%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • males or females (18 - 40 yrs)
  • no injuries of the lower extremity in the past 6 months prior to participation
  • recreationally active
  • in good health upon entry into the study
  • willing to volunteer for the present project.

Exclusion criteria

Exclusion Criteria:

  • lower extremity injury within the last 6 months
  • circulatory, vestibular or any contradiction to cryotherapy including Raynaud's disease
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
26 participants (actual)

Study arms

  • Experimental
    Cryotherapy

    The subjects will be exposed to a cold (\~ 12° C) water immersion tub at the umbilical level for 20 minutes.

    Other: Cryotherapy

  • Placebo comparator
    Control

    The subjects will be exposed to a non-cold (\~ 26° C) water immersion tub at the umbilical level for 20 minutes.

    Other: Control

Interventions

  • OtherCryotherapy

    The subjects will be exposed to a cold (\~ 12° C) water immersion tub at the umbilical level for 20 minutes.

  • OtherControl

    The subjects will be exposed to a non-cold (\~ 26° C) water immersion tub at the umbilical level for 20 minutes.

06

What researchers measure

Primary outcomes

  1. Knee frontal plane moments

    Knee frontal plane loading will be calculated using inverse dynamics based on the ground reaction force data from a force plate and with kinematic data recorded by high speed cameras. Kinematics and kinetics data will be taken during running at 4m/s from each participant prior and after the intervention.

    Time frame: 20 minutes

07

Study locations

1 site
  • Human Performance Laboratory, University of Calgary
    Calgary, Alberta T2N 1N4, Canada
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 16, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01740661
Lead sponsor
University of Calgary
Responsible party
Claudiane Fukuchi (BSc, PT, University of Calgary) — Principal investigator
First posted
Dec 4, 2012
Start date
Nov 2012
Primary completion
Dec 2012
Completion
Jan 2013
Last update
Apr 16, 2014
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2013. You cannot join it, but the record below documents what was studied.

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