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CompletedNCT01716286Updated May 11, 2016

Neural Correlates of an Olive Oil Essence

An interventional study of low fat vs. essence yoghurt in Neural Correlated of Different Foods, sponsored by University Hospital Tuebingen. Completed at 1 site in Germany. Open to male participants aged 20 Years to 33 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-05-11.

Sponsored by University Hospital Tuebingen · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
11
Allocation
Randomized
Ages
20 Years to 33 Years
Sex
Male
01

Study summary

The aim of the current study was to investigate the effect of a low fat meal in comparison to a low fat meal dosed with the fatfree essence of olive oil.

02

Conditions studied

  • Neural Correlated of Different Foods
03

In context

Lead sponsor

University Hospital Tuebingen is the lead sponsor of 476 studies on the registry; 104 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 33 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • male
  • heatly

Exclusion criteria

Exclusion Criteria:

  • lactose intolerance
  • fMRI cotraindications
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
11 participants (actual)

Study arms

  • Experimental
    yoghurt type

    low fat yoghurt vs. essence yoghurt

    Dietary Supplement: low fat vs. essence yoghurt

Interventions

  • Dietary supplementlow fat vs. essence yoghurt
06

What researchers measure

Primary outcomes

  1. change in brain activity (cerebral blood flow change after yogurt intake)

    Time frame: 30 minutes before as well as 30 minutes and 120 minutes after yoghurt intake

07

Study locations

1 site
  • University Clinic of Tuebingen, MEG Center
    Tuebingen, 72076, Germany
08

References and documents

Publications

  • Frank S, Linder K, Fritsche L, Hege MA, Kullmann S, Krzeminski A, Fritsche A, Schieberle P, Somoza V, Hinrichs J, Veit R, Preissl H. Olive oil aroma extract modulates cerebral blood flow in gustatory brain areas in humans. Am J Clin Nutr. 2013 Nov;98(5):1360-6. doi: 10.3945/ajcn.113.062679. Epub 2013 Sep 11. PubMed 24025630 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 11, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01716286
Lead sponsor
University Hospital Tuebingen
Collaborators
German Research Foundation, German Federation of Industrial Research Associations, Zentrum für Ernährungsmedizin und Prävention, German Center for Diabetes Research, University of Hohenheim, Ludwig-Maximilians - University of Munich
Responsible party
Sabine Frank (Principal Investigator, University Hospital Tuebingen) — Principal investigator
First posted
Oct 29, 2012
Start date
Feb 2012
Primary completion
Mar 2012
Completion
Mar 2012
Last update
May 11, 2016

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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