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CompletedNCT01712750Updated Oct 26, 2012

Near-Infrared Spectroscopic (NIRS) Tissue Oxygen Saturation and the Vascular Occlusion Test in Cardiac Surgery Patients

An observational study in Vascular Occlusion Test, sponsored by London Health Sciences Centre. Completed at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-10-26.

Sponsored by London Health Sciences Centre · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
13
Ages
18 Years and older
Sex
All
01

Study summary

Tissue oxygen saturation (StO2) and its recovery during a vascular occlusion test (VOT) will be measured in elective cardiac surgery patients undergoing cardiopulmonary bypass using a non-invasive near infrared spectrometry (NIRS) machine. The purpose of this study is to determine whether changes in VOT measurements occur in patients during cardiac surgery.

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Conditions studied

  • Vascular Occlusion Test

Keywords

  • Regional tissue oximetry
  • Cardiopulmonary bypass
  • Cardiac surgical procedures
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In context

Lead sponsor

London Health Sciences Centre is the lead sponsor of 39 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Elective cardiac surgery patients undergoing coronary artery bypass and valve surgery using cardiopulmonary bypass.

Inclusion criteria

  • Adult, elective cardiac surgery patients
  • Procedure using cardiopulmonary bypass

Exclusion criteria

Exclusion Criteria:

  • Contraindication to pneumatic cuff inflation
  • Pregnant
  • Significant peripheral vascular disease of the arms
  • Emergency surgery
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
13 participants (actual)

Groups and cohorts

  • VOT on bypass
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What researchers measure

Primary outcomes

  1. VOT reperfusion slope

    Reperfusion slope as measured during vascular occlusion test in units of %/s

    Time frame: Intra-operative (within 12 hours)

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Study locations

1 site
  • London Health Sciences Centre
    London, Ontario N6A 5A5, Canada
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 26, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01712750
Lead sponsor
London Health Sciences Centre
First posted
Oct 24, 2012
Start date
Feb 2011
Completion
Sep 2011
Last update
Oct 26, 2012

Study contacts

John M Murkin, MD, FRCPC
principal investigator · London Health Sciences Centre

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2012. You cannot join it, but the record below documents what was studied.

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