An observational study in Suppurative Osteomyelitis of Jaw and Potential Abnormality of Glucose Tolerance, sponsored by West China College of Stomatology. Completed at 1 site in China. Open to participants aged 1 Month to 83 Years. Per ClinicalTrials.gov, last updated 2012-08-22.
Sponsored by West China College of Stomatology · Observational
Clinically, recurrence and life-threatening complications are challenging problems for chronic suppurative osteomyelitis of the jaw. There is no quantitative analysis or report about the causes of or risk factors for the two problems. Doctors identify the causes or risk factors only through clinical experience. The investigators performed a retrospective study of 322 patients with chronic suppurative osteomyelitis of the jaw. The risk factors for the above mentioned two problems were analyzed by logistic regression analysis. The investigators found that some of the patients' general conditions, including age, admission temperature, admission white blood cell count, pre-admission antibiotic administration without consultation, location of the lesion, and general patient condition, were the risk factors. The results indicate that doctors should be mindful of those risk factors and that the management should be more aggressive when the above risk factors are present.
This is a retrospective study of 322 patients hospitalized with CSOJ. The socio-demographic and clinical characteristics were recorded. The risk factors for the above two problems were analyzed by logistic regression analysis. Frequency and percentage were used to indicate descriptive research factors. A univariate logistic regression analysis was performed to calculate the odds ratio (OR) and to identify preliminary risk factors. The preliminary risk factors were further identified by multivariate logistic regression analysis.
West China College of Stomatology is the lead sponsor of 4 studies on the registry; 1 is open to participants now.
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Patients with a diagnosis of CSOJ who were admitted to our hospital from 1980 to 2009 were investigated. Ultimately, 322 patients were enrolled in the study of life-threatening complications.Patients were divided into four classes according to their age (years): \<6, 6-18, 19-65, >65.
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Exclusion Criteria:
Risk factors associated with recurrence and life-threatening complications for patients hospitalized with chronic suppurative osteomyelitis of the jaw
An age from 6-18 years or \> 65 years, pre-admission antibiotic administration, a lesion at the mandibular ramus, concurrent maxillofacial space infection (MSI), and conservation of pathogenic teeth were found to be risk factors for recurrence. An age \> 65 years, admission temperature \> 39 oC, admission white blood cell (WBC) count \>15×109/L, pre-admission antibiotic administration, concurrent MSI, pre-existing diabetes, and respiratory difficulty were found to be risk factors for life-threatening complications.
Time frame: 30 years
The record gives a start of Jan 1980, a primary completion of Jan 2009 and a completion of May 2009. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Aug 2012. You cannot join it, but the record below documents what was studied.
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West China College of Stomatology