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CompletedNCT01668212Updated Jun 24, 2013

Perifollicular Doppler in Natural Cycle In Vitro Fertilization

An observational study in Infertility, sponsored by Clinique Ovo. Completed at 1 site in Canada. Open to female participants aged 18 Years to 38 Years. Per ClinicalTrials.gov, last updated 2013-06-24.

Sponsored by Clinique Ovo · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
160
Ages
18 Years to 38 Years
Sex
Female
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Study summary

Perifollicular Doppler could reflect the quality of the follicle's vascularization and, consequently, the one of the oocyte that ensues from it. Perifollicuar Doppler is the analysis, in ultrasound, of the blood flow in vessels surrounding the follicle.

The goal of this study is to evaluate if there is a link, in natural cycle In Vitro Fertilization, between the quality of the vascularization and the one of the oocyte, the embryo and the pregnancy.

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Conditions studied

  • Infertility

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03

In context

Infertility

2,506 studies on the registry are indexed under Infertility; 407 are open to participants now.

This study's enrollment of 160 is below the median of 200 across 714 observational studies indexed under Infertility.

Browse Infertility studies →

Lead sponsor

Clinique Ovo is the lead sponsor of 35 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 38 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Women following In Vitro Fertilization cycle

Inclusion criteria

  • Patient with a natural In Vitro Fertilization cycle.
  • Patient under 38 years old
  • Body mass indice under 35
  • Ovulatory cycles between 20-35 days

Exclusion criteria

Exclusion Criteria:

  • Patient with a stimulation In Vitro Fertilization cycle
  • Patient with a naturalIn Vitro Fertilization cycle with egg donor
  • Patient with a natural In Vitro Fertilization cycle with freezing embryo
  • Smoking patient
  • Diabetic patient
  • Patient with treatment of antihypertensive drug, anticoagulant, antiplatelet, vasodilator
  • Body mass indice over 35
  • Patient over 38 years old
  • Patient without ovulation or cycle over 35 days
  • Percutaneous Epididymal Sperm Aspiration (PESA), Testicular Sperm Extraction (TESE) or micro TESE
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
160 participants (actual)

Groups and cohorts

  • natural In Vitro Fertilization cycle

    Patient doing following natural In Vitro fertilization cycle

    Procedure: Doppler ultrasound

Interventions

  • ProcedureDoppler ultrasound

    Doppler Ultrasound

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What researchers measure

Primary outcomes

  1. Quality perifollicular doppler and quality of the oocyte

    The measurements are done twice; on days of induction and oocyte retrieval. During the blood sample collection on the day of the induction, there is also a measurement of progesterone, estradiol and luteinizing hormone (LH).

    Time frame: 2 weeks

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Study locations

1 site
  • Ovo Fertilité
    Montréal, Quebec H4P 2S4, Canada
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 24, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01668212
Lead sponsor
Clinique Ovo
Responsible party
Sponsor
First posted
Aug 20, 2012
Start date
Mar 2012
Primary completion
May 2013
Last update
Jun 24, 2013

Study contacts

Delphine Delrieu, MD
principal investigator · Clinique Ovo

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2013. You cannot join it, but the record below documents what was studied.

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