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CompletedNCT01618318GLAASUpdated Dec 5, 2013

Glasgow Asthma and Allergy Study

An observational study in Asthma and Allergy, sponsored by National Services for Health Improvement Ltd. Completed at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-12-05.

Sponsored by National Services for Health Improvement Ltd · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
105
Ages
18 Years and older
Sex
All
01

Study summary

In the past, doctors separated people with asthma into two groups, those with "allergic asthma" (about 2/3rds of people) and those with "non-allergic asthma". These labels are not much used now as the treatments for all people with asthma don't depend on this classification. However, new treatments for asthma may become available and the classification may again become important. It could be useful for clinicians to know how to identify which patients are likely to benefit from particular treatments.

Additionally, some new blood tests are becoming available and some of these might help to categorise the type of asthma people have. What the study hopes to do is to identify patient features which make a diagnosis of "allergic asthma" more likely and to see which new blood tests are most likely to be helpful in confirming this diagnosis.

02

Conditions studied

  • Asthma
  • Allergy

Keywords

  • Asthma
  • Allergy
  • Diagnosis
  • Correlation study
03

In context

Asthma

3,921 studies on the registry are indexed under Asthma; 507 are open to participants now.

This study's enrollment of 105 is below the median of 150 across 970 observational studies indexed under Asthma.

Browse Asthma studies →

Lead sponsor

National Services for Health Improvement Ltd is the lead sponsor of 2 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

People with asthma, non smoker, aged 18 and over.

Inclusion criteria

  • Male and female patients aged 18 years old and over with a diagnosis of asthma and having received at least two prescriptions for any asthma medication in the last 12 months, who have signed an informed consent form prior to initiation of any study-related procedure

Exclusion criteria

Exclusion Criteria:

  • under 18 years
  • current smokers
  • unwilling or unable to give informed consent
  • a clinical diagnosis of COPD
  • a history of anaphylaxis (skin prick test)
  • participated in any clinical study in the last 12 months
05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
105 participants (actual)

Groups and cohorts

  • General asthma population

    People with asthma, aged 18 years and over, non smoker, all severities of disease, regardless of treatment, broad inclusion and few exclusion criteria.

06

What researchers measure

Primary outcomes

  1. Serum periostin level

    This is a cross sectional study. Participants will be assessed and tests conducted at a single visit

    Time frame: 1 day

Secondary outcomes

  1. skin prick test

    Time frame: 1 day

  2. Serum total IgE

    Time frame: 1 day

  3. Blood eosinophil count

    Time frame: 1 day

  4. Blood neutrophil count

    Time frame: 1 day

  5. Blood CD4 cells that are positive for CRTh2

    Time frame: 1 day

  6. Blood eosinophils expressing CRTh2

    Time frame: 1 day

  7. Spirometry

    Time frame: 1 day

07

Study locations

1 site
  • NSHI Ltd
    Dartford, Kent DA1 5GA, United Kingdom
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 5, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01618318
Lead sponsor
National Services for Health Improvement Ltd
Collaborators
Merck Sharp & Dohme LLC
Responsible party
Sponsor
First posted
Jun 13, 2012
Start date
Jun 2012
Primary completion
Oct 2013
Completion
Oct 2013
Last update
Dec 5, 2013

Study contacts

John A Haughney, MB ChB
principal investigator · NSHI Ltd

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2013. You cannot join it, but the record below documents what was studied.

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