A Phase 4 interventional study of IUI and IUI in Mycoplasma, sponsored by Feng Pan. Status unknown. Open to male participants aged 20 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-04-10.
Sponsored by Feng Pan · Phase 4, Interventional, and Treatment
Genital ureaplasmas (Ureaplasma urealyticum and Ureaplasma parvum) and genital mycoplasmas (Mycoplasma hominis and Mycoplasma genitalium) are natural inhabitants of the male urethra contaminating the semen during ejaculation. However, these microorganisms, especially Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh), are potentially pathogenic species playing an etiologic role in both genital infections and male infertility. Despite there are many consentaneous opinions about its relationship with infertility, its correlation with sperm regular parameters is still controversially. Sperm DNA damage can negatively influence fertilization rate, embryo cleavage rate, implantation rate, pregnancy and live birth rate, and is a novel indicator for intrauterine insemination (IUI) pregnancy rate and IVF or ICSI pregnancy loss rate. Until now, there were fewer clinical researches about the relationship among Uu and/or Mh infection, sperm DNA damage, and the IUI pregnancy rate. Thus, the investigators conduct this prospective study to investigate the relationship among them.
10 studies on the registry are indexed under Mycoplasma Infections; 1 is open to participants now.
Browse Mycoplasma Infections studies →Feng Pan is the lead sponsor of 3 studies on the registry; none are open to participants now.
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Exclusion Criteria:
100 male patients whose spouse was going to conduct IUI, was not infected by mycoplasma.
Procedure: IUI
100 male patients whose spouse was going to conduct IUI, was infected by mycoplasma.
Procedure: IUI
50 fertile males were chose as control samples
intrauterine insemination
intrauterine insemination
pregnancy rate
Time frame: up to 3 monthes after IUI
sperm DNA fragmentation index (DFI)
Time frame: one month before IUI
No study locations are listed for this record.
This study is status unknown, as verified in Apr 2013. You cannot join it, but the record below documents what was studied.
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Feng Pan