An interventional study of in vitro maturation and Polar Body Biopsy with preimplantation genetic screening in Infertility, sponsored by Weill Medical College of Cornell University. Terminated at 1 site in United States. Open to female participants aged 25 Years to 42 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-11-18.
Sponsored by Weill Medical College of Cornell University · Not applicable, Interventional, and Treatment
The objectives of this study are to evaluate the clinical efficacy of Natural in vitro Fertilization and in vitro maturation.
Collection of one mature egg from a follicle in the ovary without gonadotropin medications (natural cycle IVF) results in low pregnancy rates. One way to improve natural cycle IVF is to combine this procedure with the removal of immature eggs from the ovary and mature these eggs in the laboratory ( in vitro maturation-IVM). The in vitro mature eggs are fertilized and the resultant embryos are cultured using conventional IVF techniques.
2,541 studies on the registry are indexed under Infertility; 405 are open to participants now.
This study's enrollment of 2 is below the median of 120 across 1,722 interventional studies indexed under Infertility.
Browse Infertility studies →Weill Medical College of Cornell University is the lead sponsor of 890 studies on the registry; 163 are open to participants now.
Of its 123 completed or terminated interventional studies of FDA-regulated products, 94 (76%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
in vitro maturation of immature oocytes
Procedure: in vitro maturation · Procedure: Polar Body Biopsy with preimplantation genetic screening
Maturation of immature oocytes in the laboratory following oocyte retrieval
Polar body biopsy is performed on the day that the oocyte is retrieved. Microarray analysis will will be performed and compared with FISH and microarray analysis of day 3 or day 5 biopsy.
number of oocytes retrieved and embryos generated
Time frame: 1 year
live birth rate
Time frame: 1 year
Ran from Feb 2012 to primary completion in Oct 2022, 128 months.
How these figures are worked out, and which studies are left out of them.
This study is terminated, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Weill Medical College of Cornell University →