CClinicalTrials.gg
SuspendedNCT01545973Updated Mar 7, 2012

Understanding the Physiological Implications of Scanning Kelvin Probe Measurements

An observational study in Healthy Individuals and Skin Electrical Potential, sponsored by Massachusetts General Hospital. Suspended at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-03-07.

Sponsored by Massachusetts General Hospital · Observational

Why this study was suspended
Repair of minor software glitches
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
24
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The purpose of this study is to evaluate the effects of skin thickness, skin moisture, and sweat gland density on Scanning Kelvin Probe measurements.

Read the detailed description

The Scanning Kelvin Probe measures the electrical potential of material surfaces without actually touching it. Although this technology has been applied to non-living materials (e.g. metal and semiconductors) before, it has not been effectively applied to biological materials, much less to live human skin . This project aims to evaluate the use of Scanning Kelvin Probe to live human skin by investigating the effects of skin thickness, skin moisture, and sweat glands on Kelvin Probe measurements of electrical potential. Testing will be performed on the arms and hands of twenty four healthy individuals under different study conditions.

02

Conditions studied

  • Healthy Individuals
  • Skin Electrical Potential
03

In context

Lead sponsor

Massachusetts General Hospital is the lead sponsor of 2,536 studies on the registry; 446 are open to participants now.

Of its 214 completed or terminated interventional studies of FDA-regulated products, 161 (75%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Healthy Volunteers

Inclusion criteria

  • "Healthy" is defined as not having a chronic medical condition requiring daily medications (hypertension, diabetes, hypothyroidism, etc)

Exclusion criteria

Exclusion Criteria:

  • autonomic disorders (sweating irregularities), skin disorders, extensive burns/scars on the hand, tremors, neuromuscular conditions, restless leg syndrome, movement disorders, and implanted cardiac defibrillator/pacemaker
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
24 participants (estimated)
Biospecimen retention
Samples with dna

Groups and cohorts

  • Healthy Volunteers

    Human subjects without chronic medical conditions, defined as conditions requiring chronic medication use.

    Other: Skin Moistening, Skin Denuding

Interventions

  • OtherSkin Moistening, Skin Denuding

    Application of normal saline to skin and Tape stripping of the superficial skin

06

What researchers measure

Primary outcomes

  1. Surface Electrical Potential

    The electrical potential of skin obtained from the Scanning Kelvin Probe

    Time frame: 1 day

Secondary outcomes

  1. Electrical Impedance

    Electrical impedance (measurement) obtained through another, more conventional measurement device.

    Time frame: One day

07

Study locations

1 site
  • Massachusetts General Hospital - Martinos Center for Biomedical Imaging
    Charlestown, Massachusetts 02129, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 7, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01545973
Lead sponsor
Massachusetts General Hospital
Responsible party
Andrew A. Ahn (Assistant Professor, Massachusetts General Hospital) — Principal investigator
First posted
Mar 7, 2012
Start date
Aug 2011
Primary completion
Aug 2012 (estimated)
Completion
Aug 2012 (estimated)
Last update
Mar 7, 2012

Study contacts

Andrew C. Ahn, MD, MPH
principal investigator · Massachusetts General Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is suspended, as verified in Mar 2012. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion