An interventional study of eScreen in Problematic AOD Use, sponsored by Karolinska Institutet. Completed at 1 site in Sweden. Open to participants aged 15 Years to 99 Years. Per ClinicalTrials.gov, last updated 2023-11-13.
Sponsored by Karolinska Institutet · Not applicable, Interventional, and Treatment
Objectives: This study compared the efficacy of eScreen in a two-armed randomized controlled design, measuring outcomes in terms of changes in problematic drug use up to one year after study recruitment. The eScreen brief Internet intervention for problematic alcohol and drug use offers self-screening, in-depth self-reporting, personalized feedback and treatment recommendations as well as an electronic diary. Progress over time is shown in diagrams detailing consumption levels.
Method: Participants with only problematic drug use according to the Drug Use Disorders Identification Test (DUDIT),(DUDIT >0 for both men and women) or both problematic alcohol use according to the Alcohol Use Disorders Identification Test (AUDIT), (AUDIT >7 for men and AUDIT >5 for women) and drug use were randomized to T1 (n=101) or the control group (n=101). Outcomes on alcohol and/or drug use as well as health-related symptoms were assessed after 3, 6 and 12 months.
Hypotheses that were tested in this study are 1) that both groups would reduce their drug consumption and drug-related problems at follow-ups compared to the baseline level and 2) that participants in the eScreen group would reduce their drug consumption and drug-related problems to a higher extent than participants in the control group (no intervention) at follow-ups.
Background: The aim of this study is to investigate the effects of an Internet-based screening and brief intervention (SBI) site for problematic alcohol and drug use among illicit drug users.
Method: Individuals searching for information about alcohol or drugs online who scored over 0 on the Drug Use Disorders Identification Test (DUDIT) and were 15 years or older were recruited for this trial and randomized into one group receiving Internet-based screening and brief intervention via eScreen.se(n = 101) or one assessment-only control group (n = 101). Both groups were screened at baseline and followed up at 3 and 6 months. The primary outcome measure was the DUDIT-C score and secondary outcome measures were DUDIT, AUDIT-C (Alcohol Use Disorders Identification Test-C) and AUDIT scores.Additional outcomes included the proportion of drug abstainers and those who made a clinically significant change in their alcohol and drug use. Four statistical models of analysis were used to conservatively assess results.
Karolinska Institutet is the lead sponsor of 1,146 studies on the registry; 275 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Web based self-monitoring of problematic alcohol and drug use.
Behavioral: eScreen
Untreated control group
Web based self-monitoring of problematic alcohol and drug use.
Drug Use Disorders Identification Test-Consumption (DUDIT-C)
The primary outcome measure for this trial was the total DUDIT score for the first four DUDIT questions at 3-month follow-up, as a measure of drug consumption only, referred to as the DUDIT-C.The DUDIT-C is a measure including the first four items of the DUDIT, with a minimum score of 0 and a maximum score of 16. Higher scores mean a worse outcome. Regarding the DUDIT-C, you will find information on it in the following articles. Please note that the analyses all refer to the same sample from a randomized controlled trial. Apart from the data in the two articles describing results from the current study, there are additional analyses shown in: Berman, A. H., Wennberg, P., \& Sinadinovic, K. (2015). Changes in Mental and Physical Well-Being Among Problematic Alcohol and Drug Users in 12-Month Internet-Based Intervention Trials. Psychology of Addictive Behaviors, 29(1), 97-105. doi: 10.1037/a0038420 A higher score means a worse outcome.
Time frame: 3 months
Drug Use Disorders Identification Test (DUDIT)
The total DUDIT score at 3-month follow-up, as a summarized measure of drug use (including drug consumption and drug-related problems). The DUDIT, an 11-item scale, has a minimum score of 0 and a maximum score of 44. Higher scores mean a worse outcome.
Time frame: 3 months
Alcohol Use Disorders Identification Test - Consumption (AUDIT-C)
The total AUDIT score for the first three AUDIT questions at 3-month follow-up, as a measure of alcohol consumption only, referred to as the AUDIT-C. The AUDIT-C, a 3-item scale, has a minimum score of 0 and a maximum score of 12. Higher scores mean a worse outcome.
Time frame: 3 months
Alcohol Use Disorders Identification Test - AUDIT
The total AUDIT score at 3-month follow-up, as a summarized measure of alcohol use (including alcohol consumption and alcohol-related problems). The AUDIT, an 10-item scale, has a minimum score of 0 and a maximum score of 40. Higher scores mean a worse outcome.
Time frame: 3 months
Drug Use Disorders Identification Test-Consumption (DUDIT-C)
The total DUDIT score for the first four DUDIT questions at 6-month follow-up, as a measure of drug consumption only, referred to as the DUDIT-C.The DUDIT-C is a measure including the first four items of the DUDIT, with a minimum score of 0 and a maximum score of 16. Higher scores mean a worse outcome.
Time frame: 6 months
Drug Use Disorders Identification Test (DUDIT)
The total DUDIT score at 6-month follow-up, as a summarized measure of drug use (including drug consumption and drug-related problems). The DUDIT, an 11-item scale, has a minimum score of 0 and a maximum score of 44. Higher scores mean a worse outcome.
Time frame: 6 months
Alcohol Use Disorders Identification Test-Consumption (AUDIT-C)
The total AUDIT score for the first three AUDIT questions at 6-month follow-up, as a measure of alcohol consumption only, referred to as the AUDIT-C. The AUDIT-C, a 3-item scale, has a minimum score of 0 and a maximum score of 12. Higher scores mean a worse outcome.
Time frame: 6 months
Alcohol Use Disorders Identification Test (AUDIT)
The total AUDIT score at 6-month follow-up, as a summarized measure of drug use (including alcohol consumption and alcohol-related problems). The AUDIT, an 10-item scale, has a minimum score of 0 and a maximum score of 40. Higher scores mean a worse outcome.
Time frame: 6 months
Drug Use Disorders Identification Test-Consumption (DUDIT-C)
The total DUDIT score for the first four DUDIT questions at 12-month follow-up, as a measure of drug consumption only, referred to as the DUDIT-C.The DUDIT-C is a measure including the first four items of the DUDIT, with a minimum score of 0 and a maximum score of 16. Higher scores mean a worse outcome.
Time frame: 12 months
Drug Use Disorders Identification Test (DUDIT)
The total DUDIT score at 12-month follow-up, as a summarized measure of drug use (including drug consumption and drug-related problems). The DUDIT, an 11-item scale, has a minimum score of 0 and a maximum score of 44. Higher scores mean a worse outcome.
Time frame: 12 months
Alcohol Use Disorders Identification Test-Consumption (AUDIT-C)
The total AUDIT score for the first three AUDIT questions at 12-month follow-up, as a measure of alcohol consumption only, referred to as the AUDIT-C. The AUDIT-C, a 3-item scale, has a minimum score of 0 and a maximum score of 12. Higher scores mean a worse outcome.
Time frame: 12 months
Alcohol Use Disorders Identification Test (AUDIT)
The total AUDIT score at 12-month follow-up, as a summarized measure of drug use (including alcohol consumption and alcohol-related problems). The AUDIT, an 10-item scale, has a minimum score of 0 and a maximum score of 40. Higher scores mean a worse outcome.
Time frame: 12 months
| Milestone | eScreen | Control Group |
|---|---|---|
| Started | 101 | 101 |
| Completed | 33 | 33 |
| Not completed | 68 | 68 |
| Withdrew: Lost to follow-up | 68 | 68 |
| Milestone | eScreen | Control Group |
|---|---|---|
| Started | 101 | 101 |
| Completed | 27 | 35 |
| Not completed | 74 | 66 |
| Withdrew: Lost to follow-up | 74 | 66 |
| Milestone | eScreen | Control Group |
|---|---|---|
| Started | 101 | 101 |
| Completed | 32 | 34 |
| Not completed | 69 | 67 |
| Withdrew: Lost to follow-up | 69 | 67 |
The primary outcome measure for this trial was the total DUDIT score for the first four DUDIT questions at 3-month follow-up, as a measure of drug consumption only, referred to as the DUDIT-C.The DUDIT-C is a measure including the first four items of the DUDIT, with a minimum score of 0 and a maximum score of 16. Higher scores mean a worse outcome. Regarding the DUDIT-C, you will find information on it in the following articles. Please note that the analyses all refer to the same sample from a randomized controlled trial. Apart from the data in the two articles describing results from the current study, there are additional analyses shown in: Berman, A. H., Wennberg, P., \& Sinadinovic, K. (2015). Changes in Mental and Physical Well-Being Among Problematic Alcohol and Drug Users in 12-Month Internet-Based Intervention Trials. Psychology of Addictive Behaviors, 29(1), 97-105. doi: 10.1037/a0038420 A higher score means a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Drug Use Disorders Identification Test-Consumption (DUDIT-C) | 4.8 ± 3.9 | 4.5 ± 4.1 |
The total DUDIT score at 3-month follow-up, as a summarized measure of drug use (including drug consumption and drug-related problems). The DUDIT, an 11-item scale, has a minimum score of 0 and a maximum score of 44. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Drug Use Disorders Identification Test (DUDIT) | 12.0 ± 12.6 | 10.6 ± 12.1 |
The total AUDIT score for the first three AUDIT questions at 3-month follow-up, as a measure of alcohol consumption only, referred to as the AUDIT-C. The AUDIT-C, a 3-item scale, has a minimum score of 0 and a maximum score of 12. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Alcohol Use Disorders Identification Test - Consumption (AUDIT-C) | 6.9 ± 3.1 | 6.7 ± 3.4 |
The total AUDIT score at 3-month follow-up, as a summarized measure of alcohol use (including alcohol consumption and alcohol-related problems). The AUDIT, an 10-item scale, has a minimum score of 0 and a maximum score of 40. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Alcohol Use Disorders Identification Test - AUDIT | 18.5 ± 10.1 | 17.7 ± 10.9 |
The total DUDIT score for the first four DUDIT questions at 6-month follow-up, as a measure of drug consumption only, referred to as the DUDIT-C.The DUDIT-C is a measure including the first four items of the DUDIT, with a minimum score of 0 and a maximum score of 16. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Drug Use Disorders Identification Test-Consumption (DUDIT-C) | 4.7 ± 4.2 | 4.2 ± 4.1 |
The total DUDIT score at 6-month follow-up, as a summarized measure of drug use (including drug consumption and drug-related problems). The DUDIT, an 11-item scale, has a minimum score of 0 and a maximum score of 44. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Drug Use Disorders Identification Test (DUDIT) | 11.6 ± 12.8 | 10.4 ± 12.2 |
The total AUDIT score for the first three AUDIT questions at 6-month follow-up, as a measure of alcohol consumption only, referred to as the AUDIT-C. The AUDIT-C, a 3-item scale, has a minimum score of 0 and a maximum score of 12. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) | 6.5 ± 3.3 | 6.5 ± 3.4 |
The total AUDIT score at 6-month follow-up, as a summarized measure of drug use (including alcohol consumption and alcohol-related problems). The AUDIT, an 10-item scale, has a minimum score of 0 and a maximum score of 40. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Alcohol Use Disorders Identification Test (AUDIT) | 17.4 ± 10.7 | 17.3 ± 10.7 |
The total DUDIT score for the first four DUDIT questions at 12-month follow-up, as a measure of drug consumption only, referred to as the DUDIT-C.The DUDIT-C is a measure including the first four items of the DUDIT, with a minimum score of 0 and a maximum score of 16. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Drug Use Disorders Identification Test-Consumption (DUDIT-C) | 4.4 ± 4.2 | 4.0 ± 4.1 |
The total DUDIT score at 12-month follow-up, as a summarized measure of drug use (including drug consumption and drug-related problems). The DUDIT, an 11-item scale, has a minimum score of 0 and a maximum score of 44. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Drug Use Disorders Identification Test (DUDIT) | 11.0 ± 12.8 | 9.9 ± 12.2 |
The total AUDIT score for the first three AUDIT questions at 12-month follow-up, as a measure of alcohol consumption only, referred to as the AUDIT-C. The AUDIT-C, a 3-item scale, has a minimum score of 0 and a maximum score of 12. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) | 6.3 ± 3.3 | 6.5 ± 3.4 |
The total AUDIT score at 12-month follow-up, as a summarized measure of drug use (including alcohol consumption and alcohol-related problems). The AUDIT, an 10-item scale, has a minimum score of 0 and a maximum score of 40. Higher scores mean a worse outcome.
| units on a scale | eScreen | Control Group |
|---|---|---|
| Alcohol Use Disorders Identification Test (AUDIT) | 16.9 ± 10.8 | 17.1 ± 10.5 |
Collected over 13 months from baseline recruitment.. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| eScreen | — | 0/101 (0%) | 0/101 (0%) |
| Control Group | — | 0/101 (0%) | 0/101 (0%) |
All individuals who have registered for the study and registered mandatory baseline data have been included in the baseline analyses.
| Age, Categorical(Participants) | eScreen | Control Group | Total |
|---|---|---|---|
| <=18 years | 5 | 4 | 9 |
| Between 18 and 65 years | 95 | 95 | 190 |
| >=65 years | 1 | 2 | 3 |
| Age, Continuous(years) | eScreen | Control Group | Total |
|---|---|---|---|
| Mean | 33.16 ± 13.34 | 31.93 ± 12.37 | 32.54 ± 12.84 |
| Sex: Female, Male(Participants) | eScreen | Control Group | Total |
|---|---|---|---|
| Female | 48 | 42 | 90 |
| Male | 53 | 59 | 112 |
| Region of Enrollment(participants) | eScreen | Control Group | Total |
|---|---|---|---|
| Sweden | 101 | 101 | 202 |
The record gives a start of Sep 2009, a primary completion of Apr 2011 and a completion of May 2012. It does not say whether these dates are actual or estimated.
Results were first posted in Sep 2020, 9 years 5 months after primary completion.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.