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CompletedNCT01512238Updated Oct 1, 2014

Improvement of Intentional and Unintentional Non-adherence in the Elderly

An observational study in Medication Adherence, sponsored by University of Aarhus. Completed. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2014-10-01.

Sponsored by University of Aarhus · Observational

Study type
Observational
Time perspective
Retrospective
Enrollment
630
Ages
65 Years and older
Sex
All
01

Study summary

The purpose is to study if different factors influence medicine adherence in elderly people. In this study number of generic substitution and use of non-prescription drugs, herbal medicine and dietary supplement is in focus.

Read the detailed description

The purpose of this study is to describe in the elderly:

  1. Association between medicine adherence and number of generic substitution
  2. Association between medicine adherence and use of non-prescription drugs, herbal medicine and dietary supplements and interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements'
  3. Intentional and unintentional non-adherence

Some of the data in the present study were originally collected as part of a major research project 'Methods for Improving Compliance with Medicine Intake' (MICMI). The study sample of 945 persons was randomly selected into three groups: two intervention groups and one control group. Interventions were pharmaceutical care and an electronic reminder system. All groups were followed for one year.

Data in the present study is from the pharmaceutical care group and the control group, and is descriptive.

02

Conditions studied

  • Medication Adherence

Keywords

  • Medicine adherence
  • Drug substitution
  • Herb-drug interaction
  • Herbal medicine
  • Dietary supplements
  • Over-the-counter products
  • On-line prescription records
  • Personal electronic medicine profile
  • Intentional non-adherence
  • Unintentional non-adherence
03

In context

Lead sponsor

University of Aarhus is the lead sponsor of 1,274 studies on the registry; 183 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Persons aged 65 years or older, living in their own homes without assistance to medicine administration in the Municipality of Aarhus, Denmark and who were in long-term treatment with > 4 prescription drugs at the beginning of the project

Inclusion criteria

  • Aged 65 years or older
  • Living in their own homes
  • Without assistance to medicine administration
  • Living in the Municipality of Aarhus, Denmark
  • Long-term treatment with > 4 prescription drugs

Exclusion criteria

Exclusion Criteria:

05

Study design

Time perspective
Retrospective
Enrollment
630 participants (actual)

Groups and cohorts

  • Pharmaceutical care

    Other: Pharmaceutical care

  • Control

Interventions

  • OtherPharmaceutical care

    Information about medicine, sideeffect, adherence

    Also known as: Pharmaceutical Services

06

What researchers measure

Primary outcomes

  1. Medicine adherence

    Time frame: One year

Secondary outcomes

  1. Number of generic substitution

    Time frame: One year

  2. Use of non-prescription drugs, herbal medicine and dietary supplements and frequency of interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements'

    Time frame: Actually day

  3. Intentional and unintentional non-adherence association with generic substitution and use of non-prescription drugs, herbal medicine and dietary supplements

    Time frame: One year

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 1, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01512238
Lead sponsor
University of Aarhus
Responsible party
Sponsor
First posted
Jan 19, 2012
Start date
Feb 2010
Primary completion
Jan 2011
Completion
Nov 2013
Last update
Oct 1, 2014

Study contacts

Else Marie S Damsgaard, Professor
study chair · Aarhus University Hospital
Ishay Barat, Ph.D.
study chair · Horsens Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2013. You cannot join it, but the record below documents what was studied.

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