An interventional study of lidocaine and normal saline in Drug Usage, sponsored by Ajou University School of Medicine. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2012-07-16.
Sponsored by Ajou University School of Medicine · Not applicable, Interventional, and Treatment
When not using neuromuscular blocking agent, even at optimal dosage, target-controlled infusion (TCI) of propofol and remifentanil occasionally produce unsatisfactory intubating conditions. Therefore, the investigators evaluated that the effect of tracheal lidocaine on the intubating conditions for tracheal intubation during anesthesia induction of propofol and remifentanil TCI without neuromuscular blocking agent in day-case anesthesia.
Anesthesia was induced with propofol-remifentanil TCI with the effect-site concentration of 5μg/ml and 5ng/ml, respectively. After TCI, 3 ml of normal saline or 3 ml of 4% lidocaine was instilled to larynx and trachea, following intubation was performed.
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This study's enrollment of 50 is below the median of 80 across 732 interventional studies indexed under Disease.
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3 ml of normal saline was instilled to larynx and trachea
Drug: lidocaine
3 ml of 4% lidocaine was instilled to larynx and trachea before endotracheal intubation
Drug: normal saline
3 ml of 4% lidocaine was instilled to larynx and trachea
Also known as: 4%lidocaine
3 ml of normal saline was instilled to larynx and trachea before endotracheal intubation
Also known as: control
Overall acceptable conditions for tracheal intubation
Four minutes after start of propofol-remifentanil TCI, 3 ml of normal saline or 3 ml of 4% lidocaine was instilled to larynx and trachea, and one minute later, intubation was performed in double-blinded fashion.
Time frame: baseline from 5 min of TCI was maintained
This study is completed, as verified in Jul 2012. You cannot join it, but the record below documents what was studied.
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Ajou University School of Medicine