A Phase 2 interventional study of Inhalation gas and Inhalation Nitrogen/Oxygen in Pulmonary Disease, Chronic Obstructive, sponsored by Air Liquide SA. Terminated at 1 site in Germany. Open to participants aged 45 Years to 75 Years. Per ClinicalTrials.gov, last updated 2014-08-11.
Sponsored by Air Liquide SA · Phase 2, Interventional, and Treatment
The purpose of this study is to evaluate effects of inspired gas mixtures on the distance walked by patients with severe Chronic Obstructive Pulmonary Disease (COPD) during a Six-Minute Walk test.
the purpose of this study is to evaluate the distance walked by patients with severe Chronic Obstructive Pulmonary Disease (COPD) during a Six-Minute Walk test (6MWT) while breathing Helium/Oxygen 65%/35% compared to either breathing Nitrogen/Oxygen 65%/35% or receiving Non-Invasive Ventilation (NIV) with a FiO2 of 0.35 and to evaluate exercise related symptoms
4,131 studies on the registry are indexed under Pulmonary Disease, Chronic Obstructive; 697 are open to participants now.
This study's enrollment of 3 is below the median of 70 across 2,926 interventional studies indexed under Pulmonary Disease, Chronic Obstructive.
Browse Pulmonary Disease, Chronic Obstructive studies →Air Liquide SA is the lead sponsor of 4 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Nitrogen/Oxygen (65%/35%)
Drug: Inhalation Nitrogen/Oxygen
Helium/Oxygen (65%/35%)
Drug: Inhalation Helium/Oxygen
Medicinal oxygen 100% via NIV with FiO2 of 0.35
Drug: Inhalation gas
Inhalated gas, medicinal oxygen 100% via NIV with Fi O2 0.35, one time by random, 6 minutes
Also known as: Experimental
Inhalated gas, Nitrogen/Oxygen (65%/35%), one time by random, 6 minutes
Also known as: Active Comparator
Inhalated gas, Helium/Oxygen (65%/35%) one time by random, 6 minutes
Also known as: Experimental He
Distance walked
evaluate the distance walked by patients during a Six-Minute Walk Test
Time frame: 6 minutes
Assessment of the safety of inhalation Helium/Oxygen
evaluate the safety of the administration of Helium/Oxygen 65%/35%
Time frame: 6 minutes
This study is terminated, as verified in Aug 2014. You cannot join it, but the record below documents what was studied.
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Pulmonary Disease, Chronic Obstructive→
Air Liquide SA